Skip to main content
    • Aa
    • Aa

Spatio-temporal epidemiology of Campylobacter jejuni enteritis, in an area of Northwest England, 2000–2002

  • E. GABRIEL (a1) (a2), D. J. WILSON (a1) (a3), A. J. H. LEATHERBARROW (a4), J. CHEESBROUGH (a4), S. GEE (a4), E. BOLTON (a5), A. FOX (a5), P. FEARNHEAD (a1), C. A. HART (a4) and P. J. DIGGLE (a1)...

A total of 969 isolates of Campylobacter jejuni originating in the Preston, Lancashire postcode district over a 3-year period were characterized using multi-locus sequence typing. Recently developed statistical methods and a genetic model were used to investigate temporal, spatial, spatio-temporal and genetic variation in human C. jejuni infections. The analysis of the data showed statistically significant seasonal variation, spatial clustering, small-scale spatio-temporal clustering and spatio-temporal interaction in the overall pattern of incidence, and spatial segregation in cases classified according to their most likely species-of-origin.

Corresponding author
*Author for correspondence: Dr E. Gabriel, IUT STID, Université d'Avignon, BP 1207, 84 911Avignon Cedex 9, France. (Email:
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1.GK Adak , Disease risks from foods, England and Wales, 1996–2000. Emerging Infectious Diseases 2005; 11: 365372.

2.T Humphrey , SJ O'Brien , M Madsen . Campylobacters as zoonotic pathogens: a food production perspective. International Journal of Food Microbiology 2007; 117: 237257.

3.K Jones . Campylobacters in water, sewage and the environment. Journal of Applied Microbiology 2001; 90: 68S79S.

4.DJ Wilson , Tracing the source of campylobacteriosis. PLoS Genetics 2008; 4: e1000203.

5.KE Dingle , Multilocus sequence typing system for Campylobacter jejuni. Journal of Clinical Microbiology 2001; 39: 1423.

6.E Gabriel , PJ Diggle . Second-order analysis of inhomogeneous spatio-temporal point process data. Statistica Neerlandica 2009; 63: 4351.

7.R Eyles , Spatial and temporal patterns of Campylobacter contamination underlying public health risk in the Taieri River, New Zealand. Journal of Environmental Quality 2003; 32: 18201828.

8.N French , Spatial epidemiology and natural population structure of Campylobacter jejuni colonizing a farmland ecosystem. Environmental Microbiology 2005; 7: 11161126.

9.W Sopwith , Campylobacter jejuni multilocus sequence types in humans, northwest England, 2003–2004. Emerging Infectious Diseases 2006; 12: 15001507.

11.PJ Diggle , P Zeng , P Durr . Nonparametric estimation of spatial segregation in a multivariate point process: bovine tuberculosis in Cornwall, UK. Applied Statistics 2005; 54: 645658.

12.PJ Diggle , Second-order analysis of inhomogeneous spatial point processes using case-control data. Biometrics 2007; 63: 550557.

13.A Baddeley , J Moller , R Waagepetersen . Non- and semi-parametric estimation of interaction in inhomogeneous point patterns. Statistica Neerlandica 2000; 54: 329350.

15.W Sopwith , Enhanced surveillance of campylobacter infection in the North West of England, 1997–1999. Journal of Infection 2003; 46: 3545.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *