Skip to main content
×
Home
    • Aa
    • Aa

The seroepidemiology of varicella zoster virus among pregnant Bangladeshi and white British women in the London Borough of Tower Hamlets, UK

  • Y. S. TALUKDER (a1), G. KAFATOS (a2), A. PINOT de MOIRA (a1), J. AQUILINA (a3), S. P. PARKER (a1), N. S. CROWCROFT (a4), D. W. G. BROWN (a5) and J. BREUER (a1)...
Abstract
SUMMARY

We investigated the comparative seroepidemiology of varicella zoster virus (VZV) in pregnant women of two ethnic groups, white British and Bangladeshi, living in an inner city area of London, United Kingdom. Women aged 16–45 years were recruited from antenatal clinics of the Royal London Hospital in the Borough of Tower Hamlets. Complete data were obtained from 275 white British and 765 Bangladeshi women. VZV antibody prevalence was 93·1% (95% CI 89·4–95·8) and 86·0% (95% CI 83·3–88·4) respectively. Women who were born in Bangladesh and lived there at least until the age of 15 years had the lowest odds of being immune (OR 0·37, 95% CI 0·22–0·63). This implies they will have an increased risk of varicella during pregnancy. Women arriving in the United Kingdom in adulthood should be screened routinely during pregnancy and vaccination offered postpartum if they are susceptible.

Copyright
Corresponding author
*Author for correspondence: Ms. Y. S. Talukder, Centre for Infectious Disease, Institute of Cell and Molecular Science, Queen Mary School of Medicine and Dentistry, 4 Newark St, London E1 2AT, UK. (Email: ingrej@gmail.com)
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1. CK Fairley , E Miller . Varicella-zoster virus epidemiology – a changing scene? Journal of Infectious Diseases 1996; 174 (Suppl. 3): S314S319.

5. B Lee . Review of varicella zoster seroepidemiology in India and Southeast Asia. Tropical Medicine and International Health 1998; 3: 886890.

6. D Nathwani , Varicella infections in pregnancy and the newborn. A review prepared for the UK Advisory Group on Chickenpox on behalf of the British Society for the Study of Infection. Journal of Infection 1998; 36 (Suppl. 1): 5971.

7. G Enders , Consequences of varicella and herpes zoster in pregnancy: prospective study of 1739 cases. Lancet 1994; 343: 15481551.

8. SG Paryani , AM Arvin . Intrauterine infection with varicella-zoster virus after maternal varicella. New England Journal of Medicine 1986; 314: 15421546.

9. AL Pastuszak , Outcome after maternal varicella infection in the first 20 weeks of pregnancy. New England Journal of Medicine 1994; 330: 901905.

11. SK Saha , Seroepidemiology of varicella-zoster virus in Bangladesh. Annals of Tropical Paediatrics 2002; 22: 341345.

12. S Thomas , J Wheeler , A Hall . Contacts with varicella or with children and protection against herpes zoster in adults: a case-control study. Lancet 2002; 360: 678.

14. NJ Gay . Analysis of serological surveys using mixture models: application to a survey of parvovirus B19. Statistics in Medicine 1996; 15: 15671573.

15. G Kafatos , N Andrews , A Nardone . Model selection methodology for inter-laboratory standardisation of antibody titres. Vaccine 2005; 23: 50225027.

16. JH Lubin , Epidemiologic evaluation of measurement data in the presence of detection limits. Environmental Health Perspective 2004; 112: 16911696.

17. RH Dworkin . Racial differences in herpes zoster and age at onset of varicella. Journal of Infectious Diseases 1996; 174: 239241.

18. K Schmader , Racial differences in the occurrence of herpes zoster. Journal of Infectious Diseases 1995; 171: 701704.

23. DP Sinha . Chickenpox – a disease predominantly affecting adults in rural West Bengal, India. International Journal of Epidemiology 1976; 5: 367374.

24. S Wagenpfeil , Empirical data on the varicella situation in Germany for vaccination decisions. Clinical Microbiology and Infection 2004; 10: 425430.

28. G Enders , EM. Miller Varicella and herpes zoster in pregnancy and the newborn. In: A Gershon , AM Arvin eds. Varicella Zoster Virus: Virology and Clinical Management. Cambridge University Press, 2000, pp. 317395.

30. KJ McKenzie , NS Crowcroft . Race, ethnicity, culture, and science. British Medical Journal 1994; 309: 286287.

32. JN Longfield , Varicella outbreaks in Army recruits from Puerto Rico. Varicella susceptibility in a population from the tropics. Archives of Internal Medicine 1990; 150: 970973.

33. E Miller , R Marshall , J Vurdien . Epidemiology, outcome and control of varicella-zoster infection. Reviews in Medical Microbiology 1993; 4: 222230.

34. A Pinot de Moira , WJ Edmunds , J Breuer . The cost-effectiveness of antenatal varicella screening with post-partum vaccination of susceptibles. Vaccine 2006; 24: 12981307.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×