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    Pati, Niladri Vishwakarma, Vikalp Selvaraj, Sathish kumar Dash, Sabyasachi Saha, Bhaskar Singh, Neera and Suar, Mrutyunjay 2013. Salmonella Typhimurium TTSS-2 deficient mig-14 mutant shows attenuation in immunocompromised mice and offers protection against wild-type Salmonella Typhimurium infection. BMC Microbiology, Vol. 13, Issue. 1, p. 236.

    Pardon, P. Sanchis, R. Marly, J. Lantier, F. Guilloteau, L. Buzoni-Gatel, D. Oswald, I.P. Pépin, M. Kaeffer, B. Berthon, P. and Popoff, M.Y. 1990. Experimental ovine salmonellosis (Salmonella Abortusovis): Pathogenesis and vaccination. Research in Microbiology, Vol. 141, Issue. 7-8, p. 945.

    Vladoianu, Ion-Rusan Chang, Hernán R. and Pechère, Jean-Claude 1990. Expression of host resistance to Salmonella typhi and Salmonella typhimurium: bacterial survival within macrophages of murine and human origin. Microbial Pathogenesis, Vol. 8, Issue. 2, p. 83.

    Vladoianu, I.R. and Taidi-Nakissa, Behnaz 1978. Efficacité de la vaccination orale avec S. typhimurium streptomycino-dépendante vivante, chez la souris C57BL/6. Journal of Biological Standardization, Vol. 6, Issue. 1, p. 45.


Experimental model of oral antityphoid vaccination with live streptomycin-dependent Salmonella typhimurium in C57BL/6 mice

  • I. R. Vladoianu (a1) and F. Dubini (a1)
  • DOI:
  • Published online: 01 May 2009

The present experimental model offered the opportunity to study particular aspects concerning the avirulence stability of live streptomycin-dependent (Sm D) Salmonella vaccines, under conditions resembling human enteric fever. The results seem to indicate that, in practice, the risk of reversion to a virulent form during oral antityphoid vaccination with Sm D strains remains slight even after the interruption of concomitant streptomycin administration.

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L.S. Baron & S. B. Formal (1960). Immunization studies with living vaccine of Salmonella typhimurium. Proceedings of the Society for Experimental Biology and Medicine 104, 565–7.

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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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