Skip to main content Accessibility help
×
×
Home

Four cases of acute flaccid paralysis associated with chikungunya virus infection

  • S. S. SINGH (a1), S. P. MANIMUNDA (a2), A. P. SUGUNAN (a2), SAHINA (a1) and P. VIJAYACHARI (a2)...
Summary

The recent epidemic of chikungunya fever (2005–2006) in India has affected millions of people. The Andaman and Nicobar Islands, an archipelago situated in the Bay of Bengal 1200 km from peninsular India, also witnessed an outbreak of chikungunya fever starting in July 2006 which affected thousands of people. Chikungunya fever classically manifests as high fever, myalgia, arthralgia and arthritis and in a certain percentage of cases with maculopapular rashes. However, deviation from the classical clinical features of chikungunya fever was reported in the earlier and recent epidemics. During the recent epidemic in the Andaman and Nicobar Islands we came across ten cases of flaccid limb weakness following symptoms and signs suggestive of chikungunya fever. In four subjects we confirmed the diagnosis of chikungunya virus infection by serological method (IgM ELISA method). This is the case report of those four subjects.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Four cases of acute flaccid paralysis associated with chikungunya virus infection
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Four cases of acute flaccid paralysis associated with chikungunya virus infection
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Four cases of acute flaccid paralysis associated with chikungunya virus infection
      Available formats
      ×
Copyright
Corresponding author
*Author for correspondence: Dr P. Vijayachari, Officer-in-charge, Regional Medical Research Centre (ICMR), Post bag no.13, Dollygunj, Port Blair-744101, Andaman and Nicobar Islands, India. (Email: pblicmr@sancharnet.in)
References
Hide All
1. Quatresous, I. Chikungunya outbreak in Reunion, a French overseas department. Eurosurveillance 2006; 11 (2): 060202.
2. Chatterjee, SN, et al. Virological investigation of cases with neurological complications during the outbreak of haemorrhagic fever in Calcutta. Journal of the Indian Medical Association 1965; 45: 314316.
3. Jadhav, M, et al. Chikungunya disease in infants and children in Vellore: a report of clinical and haematological features of virologically proved cases. Indian Journal of Medical Research 1965; 53: 764776.
4. Thiruvengadam, KV, Kalyanasundaram, V, Rajgopal, J. Clinical and pathological studies on chikungunya fever in Madras city. Indian Journal of Medical Research 1965; 53: 729744.
5. Carey, DE, et al. The 1964 chikungunya epidemic at Vellore, South India, including observations on concurrent dengue. Transactions of the Royal Society of Tropical Medicine and Hygiene 1969; 63: 434445.
6. Patrick, B, Blaise, G. Chikungunya: an epidemic in real time. Lancet Infectious Diseases 2006; 368: 258.
7. Kalantri, SP, Joshi, R, Riley, LW. Chikungunya epidemic: an Indian perspective. National Medical Journal of India. 2006; 19: 315322.
8. Manimunda, SP, et al. Chikungunya fever, Andaman and Nicobar Islands, India. Emerging Infectious Diseases 2007; 13: 12591260.
9. Stephen, LS, Arthur, KS. Guillian–Barré Syndrome and other immune-mediated neuropathies. In: Kasper, DL, Braunwald, E, Fauci, AS, Hauser, SL, Longo, DL, Jameson, JL eds. Harrison's Principles of Internal Medicine. McGraw-Hill, 2005, pp. 25132515.
10. Schuffenecker, I, et al. Genome microevolution of chikungunya viruses causing Indian Ocean outbreak. PLOS Medicine 2006; 3: e263.
11. Yergolkar, PN, et al. Chikungunya outbreaks caused by African genotype, India. Emerging Infectious Diseases 2006; 12: 15801583.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed