Skip to main content Accessibility help
×
Home
Hostname: page-component-684899dbb8-nlvjk Total loading time: 0.296 Render date: 2022-05-22T05:53:58.453Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "useRatesEcommerce": false, "useNewApi": true }

Helicobacter antibodies in 1973 and 1994 in the adult population of Vammala, Finland

Published online by Cambridge University Press:  01 August 1997

T. U. KOSUNEN
Affiliation:
Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland
A. AROMAA
Affiliation:
Social Insurance Institution, Helsinki, and National Public Health Institute, Helsinki, Finland
P. KNEKT
Affiliation:
Social Insurance Institution, Helsinki, and National Public Health Institute, Helsinki, Finland
A. SALOMAA
Affiliation:
Vammala Health Center, Vammala, Finland
H. RAUTELIN
Affiliation:
Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland
P. LOHI
Affiliation:
Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland
O. P. HEINONEN
Affiliation:
Department of Public Health, University of Helsinki, Helsinki, Finland
Rights & Permissions[Opens in a new window]

Abstract

HTML view is not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Changes in Helicobacter pylori seroprevalence were studied determining IgG and IgA antibodies of 408 randomly selected adults aged 15–74 years living in Vammala, Finland in 1973 and of 504 similarly selected subjects in 1994. Seroprevalence increased by age at both time points. The age-adjusted seroprevalence rate was clearly lower in 1994 than in 1973 (31 vs. 56%, P=0·001). Paired serum samples of 224 subjects collected in 1973 and 1994 showed that the antibody status remained unaltered in 92%; 4% seroconverted and 4% seroreverted within the 21 years. The decrease in the seroprevalence rate in the population and the persistence of individual antibody status over two decades support a difference in H. pylori infection rates among birth cohorts over time rather than continuous acquisition of new infections with advancing age. Thus the risk of helicobacter infection in Vammala, Finland has been highest in childhood and continuously decreased at least for the last five decades.

Type
Research Article
Copyright
© 1997 Cambridge University Press
You have Access
96
Cited by

Save article to Kindle

To save this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Helicobacter antibodies in 1973 and 1994 in the adult population of Vammala, Finland
Available formats
×

Save article to Dropbox

To save this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you used this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about saving content to Dropbox.

Helicobacter antibodies in 1973 and 1994 in the adult population of Vammala, Finland
Available formats
×

Save article to Google Drive

To save this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you used this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about saving content to Google Drive.

Helicobacter antibodies in 1973 and 1994 in the adult population of Vammala, Finland
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *