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Institutional outbreaks of rotavirus diarrhoea: potential role of fomites and environmental surfaces as vehicles for virus transmission

  • Syed A. Sattar (a1), Nellie Lloyd-Evans (a1), V. Susan Springthorpe (a1) and Rama C. Nair (a2)

Summary

To assess the potential of fomites and environmental surfaces as vehicles in the transmission of rotaviral diarrhoea, disks (1 cm diameter) of various porous and non-porous materials were contaminated with about 105 plaque-forming units of the Wa strain of human rotavirus (HRV) suspended in faecal matter. The contaminated disks were then held for 10 days at either room temperature (22±2 °C) or 4°C with the relative humidity (RH) at the high (85±5%), medium (50±5%) or low (25±5%) level. Survival was longer on non-porous surfaces at the lower temperature and at lower humidity. In contrast, survival on porous surfaces was very variable; better on cotton-polyester than on poster card or paper currency on which HRV survived very poorly. These results suggest that under the right environmental conditions, HRV-contaminated objects could play a role in the transmission of rotavirus infections in hospitals, nursing homes and day-care centres.

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References

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Brandt, C. D., Kim, H. W., Yolken, R. H., Kapikian, A. Z., Arrobio, J. O., Rodriguez, W. J., Wyatt, R. G, Chanock, R. M. & Parrott, R. H. (1979). Comparative epidemiology of two rotavirus serotypes and other viral agents associated with paediatrie gastroenteritis. American Journal of Epidemiology 110, 243254.
Bryden, A. S., Davies, H. A., Hadley, R. E., Flewett, T. H., Morris, C. A. & Oliver, P. (1974). Rotavirus in the West Midlands during 1974. Lancet ii, 241243.
Champsaur, H., Henry-Amar, M., Goldszmidt, D., Prévot, J., Bourjouane, M., Questiaux, E. & Bach, C. (1984 b). Serological response to rotavirus and virus shedding: a prospective study. Journal of Infectious Diseases 149, 675682.
Champsaur, H., Questiaux, E., Prévot, J., Henry-Amar, D., Goldszmidt, D., Bourjouane, M. & Bach, C. (1984 a). Rotavirus carriage, asymptomatic infection and disease in the first two years of life. Journal of Infectious Diseases 149, 667674.
Davidson, G. P., Bishop, R. F., Townley, R. R. W., Holmes, I. H. & Ruck, B. J. (1975). Importance of a new virus in acute sporadic enteritis in children. Lancet i, 242245.
Echeverria, P., Burke, D. S., Blacklow, N. R., Cukor, G., Charoenkul, C. & Yanggratoke, S. (1983). Age specific antibody to rotavirus, Escherichia coli heat-labile enterotoxin, Norwalk virus, and hepatitis A virus in a rural community in Thailand. Journal of Clinical Microbiology 17, 923925.
Flewett, T. H. (1983). Rotaviruses in the home and hospital nursery. British Medical Journal 287, 568569.
Freij, L., Sterky, G., Wadstrom, T. & Wall, S. (1978). Child health and diarrhoeal disease in relation to water supply and use of water in African communities. Progress in Water Technology 11, 4955.
Grimwood, K., Abbott, G. D., Fergusson, D. M., Jennings, L. C. & Allan, J. M. (1983). Spread of rotavirus within families: a community based study. British Medical Journal 287, 575577.
Halvorsrud, J. & Orstavik, I. (1980). An epidemic of rotavirus-associated gastroenteritis in a nursing home for the elderly. Scandinavian Journal of Infectious Diseases 12, 161164.
Hara, M., Mukoyama, J., Tsuruhara, T., Saito, Y. & Tagaya, I. (1976). Duovirus in school children with gastroenteritis. Lancet i, 311.
Harris, J. R., Cohen, M. L. & Lippy, E. C. (1983). Water-related disease outbreaks in the United States – 1981. Journal of Infectious Diseases 148, 759762.
Haug, K. W., Orstavik, I. & Kvelstad, G. (1978). Rotavirus infections in families – a clinical find virological study. Scandinavian Journal of Infectious Diseases 10, 265269.
Hildreth, C., Thomas, M., & Ridgeway, G. L. (1981). Rotavirus infection in an obstetric unit. British Medical Journal 282, 231.
Hoh, H., Presser, W. & Wigand, R. (1983). Nosokomial-Infektion durch Rotaviren bei Erwachsennen. Deutsche Medizinische Wochenschrift 108, 15861591.
Holdaway, M. D., Kalmakoff, J., Schroeder, B. A., Wright, G. C. & Todd, B. A. (1982 b). Rotavirus infection in Otago: a serological study. New Zealand Medical Journal 95, 110112.
Holdaway, M. D., Todd, B. A., Schroeder, B. A. & Kalmakoff, J. (1982 a). Rotavirus infection in New Zealand. New Zealand Medical Journal 95, 67–69.
Holzel, H., Cubitt, W. D., McSwiggan, D. A., Sanderson, P. J. & Church, J. (1980). All outbreak of rotavirus infection among adults in a cardiology ward. Journal of Infection 2, 3337.
Huno, T., Chen, C., Wang, C., Yao, H., Fang, Z., Chou, T., Chou, Z., W, Ye., Chang, X., Den, S., Liang, X. & Chang, W. (1984). Waterborne outbreak of rotavirus diarrhoea in adults in China caused by a novel rotavirus. Lancet i, 11391142.
Ijaz, M. K., Sattar, S. A., Johnson-Lussenburg, C. M. & Springthorpe, V. S. (1985). Comparison of the airborne survival of calf rotavirus and poliovirus type 1 (Sabin) aerosolized as a mixture. Applied and Environmental Microbiology 49, 289293.
Keswick, B. H., Pickering, L. K., DuPont, H. L. & Woodward, W. E. (1983 a). Survival and detection of rotaviruses on environmental surfaces in day-care centres. Applied and Environmental Microbiology 46, 813816.
Keswick, H. H., Pickering, L. K., DuPont, H. L, & Woodward, W. E. (1983 b). Prevalence of rotavirus in children in day-care centres. Journal of Pediatrics 103. 8586.
Kim, H. W., Brant, C. D., Kapikian, A. Z., Wyatt, R. G., Arrobio, J. O., Rodriguez, W. J., Chanock, R. M. & Parrott, R. H. (1977). Human rotavirus-like agent infection. Occurrence in adult contacts of pediatric patients with gastroenteritis. Journal of the American Medical Association 28, 404407.
Konno, T., Suzuki, H., Katsushima, N., Imai, A., Tazawa, F., Kutsuzawa, T., Kitaoka, S., Sakamoto, M., Yazaki, N. & Ishida, N. (1983). Influence of temperature and relative humidity on human rotavirus infection in Japan. Journal of Infectious Diseases 147, 125128.
Lloyd-Evans, N., Sprinothorpe, V. S. & Sattar, S. A. (1986). Chemical disinfection of human rotavirus-contaminated inanimate surfaces. Journal of Hygiene, In the Press.
Lycke, E., Blomberg, J., Berg, G., Eriksson, A. & Madsen, L. (1978). Epidemic acute diarrhoea in adults associated with infantile gastroenteritis virus. Lancet ii, 10561057.
McNulty, M. S. & Logan, E. F. (1983). Longitudinal survey of rotavirus infection in calves. Veterinary Record 113, 333335.
Marrie, T. J., Lee, S. H. S., Faulkner, R. S., Ethier, J. & Young, C. H. (1982). Rotavirus infection in a geriatric population. Archives of Internal Medicine 142, 313316.
Middleton, P. J., Szymanski, M. T. & Petric, M. (1977). Viruses associated with acute gastroenteritis in young children. American Journal of Diseases in Childhood 131, 733737.
Moe, K. & Shirley, J. A. (1982). The effects of relative humidity and temperature on the survival of human rotavirus in faeces. Archives of Virology 72, 179186.
Morens, D. M., Zweighaft, R. M., Vernon, T. M., Gary, G. W., Eslien, J. J., Wood, B. T., Holman, R. C. & Dolin, R. (1979). A waterborne outbreak of gastroenteritis with secondary person-to-person spread. Lancet i, 964966.
Murphy, A. M., Albrey, M. B., & Crewe, E. B. (1977). Rotavirus infections of neonates. Lancet ii, 11491150.
Noone, C. & Banatvala, J. E. (1983). Hospital acquired rotaviral gastroenteritis in a general paediatric unit. Journal of Hospital Infection 4, 297299.
Pickering, L. K., Evans, D. G., Dupont, H. L. & Vollet, J. J. III (1981). Diarrhoea caused by Shigella, rotavirus and giardia in day-care centres: Prospective study. Journal of Pediatrics 99, 5156.
Ramia, S. & Sattar, S. A. (1979). Simian rotavirus SA-11 plaque formation in the prescence of trypsin. Journal of Clinical Microbiology 10, 609614.
Rocchi, G., Vella, S., Resta, S., Cochi, S., Donelli, G., Tangucci, F., Manichella, D., Varveri, A. & Inglese, R. (1981). Outbreak of rotavirus gastroenteritis among premature infants. British Medical Journal 283, 886.
Rossi, A., Agliano, A. M., Spanu, T., Salvaggio, E., Rossodivita, A., Chezzi, C. & La Monica, S. (1982). Incidence of rotaviruses and astroviruses in children without symptoms of gastroenteritis. Igiene Moderna 78, 230239.
Ryder, R. W., McGowan, J. E., Hatch, M. H. & Palmer, E. L. (1977). Reovirus-like agent as a cause of nosocomial diarrhoea in infants. Journal of Pediatrics 90, 698702.
Samadi, A. R., Huq, M. I. & Ahmed, Q. S. (1983). Detection of rotavirus in the handwashings of attendants of children with diarrhoea. British Medical Journal 286, 188.
Sattar, S. A., Ijaz, M. K., Johnson-Lussenburg, M. & Springthorpe, V. S. (1984). Effect of relative humidity on the airborne survival of rotavirus SA-11. Applied and Environmental Microbiology 47, 879881.
Sattar, S. A., Raphael, R. A., Lochnan, H. & Springthorpe, V. S. (1983). Rotavirus inactivation by chemical disinfectants and antiseptics used in hospitals. Canadian Journal of Microbiology 29, 14641469.
Sprinothorpe, V. S., Grenier, J. L., Lloyd-Evans, N. & Sattar, S. A. (1986). Chemical disinfection of human rotaviruses: efficacy of commercially-available products in suspension tests. Journal of Hygiene, In the Press.
Sutmoller, F., Azeredo, R. S., Lacerda, M. D., Barth, M. O., Pereira, H. G., Hoffer, E. & Schatzmayr, H. G. (1982). An outbreak of gastroenteritis caused by both rotavirus and Shigella sonnei in a private school in Rio de Janeiro. Journal of Hygiene 88, 285293.
Tan, J. A. & Schnagl, R. D. (1981). Inactivation of a rotavirus by disinfectants. Medical Journal of Australia 1, 1931.
Totterdell, B. M., Chrystie, I. L. & Banatvala, J. E. (1976). Rotavirus infections in a maternity unit. Archives of Diseases in Childhood 51, 924928.
Woode, G. N. & Bridger, J. C. (1975). Viral enteritis of calves. Veterinary Record 96. 8588.
Wyatt, R. G., James, W. D., Bohl, E. H., Theil, K. W., Saif, L. J., Kalica, R., Greenberg, H. B., Kapikian, A. Z. & Chanock, R. M. (1980). Human rotavirus type 2 cultivation in vitro. Science 207, 189191.
Yolken, R. H., Bishop, C. A., Townsend, T. R., Bolyard, E. A., Bartlett, J., Santos, G. W. & Saral, R. (1982). Infectious gastroenteritis in bone-marrow transplant recipients. New England Journal of Medicine 299, 11561161.

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