Skip to main content
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 16
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Trama, Jason P. Adelson, Martin E. and Mordechai, Eli 2007. Identification and genotyping of molluscum contagiosum virus from genital swab samples by real-time PCR and Pyrosequencing. Journal of Clinical Virology, Vol. 40, Issue. 4, p. 325.

    Agromayor, Monica Ortiz, Pablo Lopez-Estebaranz, Jose L. Gonzalez-Nicolas, Josefa Esteban, Mariano and Martin-Gallardo, Antonia 2002. Molecular epidemiology of molluscum contagiosum virus and analysis of the host-serum antibody response in Spanish HIV-negative patients. Journal of Medical Virology, Vol. 66, Issue. 2, p. 151.

    del Rosario González Hermosa, M.a and Soloeta Arechavala, Ricardo 2001. Molusco contagioso. Piel, Vol. 16, Issue. 7, p. 322.

    Thompson, Carol H. Yager, Julie A. and Van Rensburg, Izak B. 1998. Close relationship between equine and human molluscum contagiosum virus demonstrated by in situ hybridisation. Research in Veterinary Science, Vol. 64, Issue. 2, p. 157.

    Martin-Gallardo, Antonia Moratilla, Marta Funes, Juan M. Agromayor, Monica Nu�ez, Antonio Varas, Antonio J. Collado, Manuel Valencia, Alfonso Lopez-Estebaranz, Jose L. and Esteban, Mariano 1996. Sequence analysis of aMolluscum contagiosum virus DNA region which includes the gene encoding protein kinase 2 and other genes with unique organization. Virus Genes, Vol. 13, Issue. 1, p. 19.

    Nuñez, Antonio Funes, Juan M. Agromayor, Monica Moratilla, Marta Varas, Antonio Jesus Lopez-Estebaranz, Jose L. Esteban, Mariano and Martin-Gallardo, Antonia 1996. Detection and typing of molluscum contagiosum virus in skin lesions by using a simple lysis method and polymerase chain reaction. Journal of Medical Virology, Vol. 50, Issue. 4, p. 342.


    Nakamura, J. Muraki, Y. Yamada, M. Hatano, Y. and Nii, S. 1995. Analysis of molluscum contagiosum virus genomes isolated in Japan. Journal of Medical Virology, Vol. 46, Issue. 4, p. 339.

    Forghani, Bagher Oshiro, Lyndon S. Chan, Cynthia S. Hurst, Jerry W. Dennis, Juanita Darai, Gholamreza Warford, Ann L. and Cohen, Richard M. 1992. Direct detection of Molluscum contagiosum virus in clinical specimens by in situ hybridization using biotinylated probe. Molecular and Cellular Probes, Vol. 6, Issue. 1, p. 67.

    Konya, Joseph Thompson, Carol H. and De Zwart-Steffe, Rita T. 1992. Enzyme-linked immunosorbent assay for measurement of IgG antibody to Molluscum contagiosum virus and investigation of the serological relationship of the molecular types. Journal of Virological Methods, Vol. 40, Issue. 2, p. 183.

    Porter, C. D. and Archard, L. C. 1992. Characterisation by restriction mapping of three subtypes ofMolluscum contagiosum virus. Journal of Medical Virology, Vol. 38, Issue. 1, p. 1.

    Billstein, Stephan A. and Mattaliano, Vincent J. 1990. The “Nuisance” Sexually Transmitted Diseases: Molluscum Contagiosum, Scabies, and Crab Lice. Medical Clinics of North America, Vol. 74, Issue. 6, p. 1487.

    Thompson, Carol H. De Zwart-Steffe, Rita T. and Biggs, Ian M. 1990. Molecular epidemiology of Australian isolates of molluscum contagiosum. Journal of Medical Virology, Vol. 32, Issue. 1, p. 1.

    PORTER, C.D. BLAKE, N.W. ARCHARD, L.C. MUHLEMANN, M.F. ROSEDALE, N. and CREAM, J.J. 1989. Molluscum contagiosum virus types in genital and non-genital lesions. British Journal of Dermatology, Vol. 120, Issue. 1, p. 37.

    Scholz, J. Rösen-Wolff, A. Bugert, J. Reisner, H. White, M. I. Darai, G. and Postlethwaite, R. 1989. Epidemiology of molluscum contagiosum using genetic analysis of the viral DNA. Journal of Medical Virology, Vol. 27, Issue. 2, p. 87.

    Baxby, Derrick 1988. Human poxvirus infection after the eradication of smallpox. Epidemiology and Infection, Vol. 100, Issue. 03, p. 321.


Molluscum contagiosum: characterization of viral DNA and clinical features

  • C. D. Porter (a1), M. F. Muhlemann (a2), J. J. Cream (a2) and L. C. Archard (a1)
  • DOI:
  • Published online: 19 October 2009

Restriction endonuclease analysis of molluscum contagiosum virus DNA revealed two subtypes. In a study of 46 isolates from 41 patients, some with no other disorder and some with atopic dermatitis, the ratio of MCV I isolates to MCV II was 34:12. Multiple clustered lesions removed at the same time from an individual patient yielded only one type of MCV. Lesions induced by MCV I or MCV II were indistinguishable on the basis of size and form. Neither subtype was associated exclusively with lesions at certain sites or with other clinical features. Heterogeneity of DNA restriction endonuclease cleavage patterns amongst isolates of the same subtype was observed, this being greatest for MCV II.

Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

S. T. Brown , J. F. Nalley S. J. Kraus (1981). Molluscum contagiosum. Sexually Transmitted Diseases 8, 227234.

S. M. J. Chaney , K. G. Warren , J. Kettyls , A. Zbitnue & J. H. Subak-Sharpe (1983). A comparative analysis of restriction enzyme digests of the DNA of herpes simplex virus isolated from genital and facial lesions. Journal of General Virology 64, 357371.

G. Darai , H. Reisner , J. Scholz , P. Schnitzler & H. Lordacher De Ruiz (1986). Analysis of the genome of molluscum contagiosum virus by restriction endonuclease analysis and molecular cloning. Journal of Medical Virology 18, 29–39.

C. D. Porter & L. C. Archard (1987). Characterisation and physical mapping of molluscum contagiosum virus DNA and location of a sequence capable of encoding a conserved domain of epidermal growth factor. Journal of General Virology 68, 673682.

R. Postlethwaite (1970). Molluscum contagiosum: a review. Archives of Environmental Health 21, 432452.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *