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Multiple risk factors associated with a large statewide increase in cryptosporidiosis

  • A. L. VALDERRAMA (a1) (a2), M. C. HLAVSA (a3), A. CRONQUIST (a4), S. COSGROVE (a4), S. P. JOHNSTON (a3), J. M. ROBERTS (a3), M. L. STOCK (a5), L. XIAO (a3), K. XAVIER (a4) and M. J. BEACH (a3)...
Abstract
SUMMARY

Cryptosporidium species have emerged as a major cause of outbreaks of diarrhoea and have been associated with consumption of contaminated recreational and drinking water and food as well as contact with infected attendees of child-care programmes. In August 2007, the Colorado Department of Public Health and Environment detected an increase in cryptosporidiosis cases over baseline values. We conducted a case-control study to assess risk factors for infection and collected stool specimens from ill persons for microscopy and molecular analysis. Laboratory-confirmed cases (n=47) were more likely to have swallowed untreated water from a lake, river, or stream [adjusted matched odds ratio (aOR) 8·0, 95% confidence interval (CI) 1·3–48·1], have had exposure to recreational water (aOR 4·6, 95% CI 1·4–14·6), or have had contact with a child in a child-care programme or in diapers (aOR 3·8, 95% CI 1·5–9·6). Although exposure to recreational water is commonly implicated in summertime cryptosporidiosis outbreaks, this study demonstrates that investigations of increased incidence of cases in summer should also examine other potential risk factors. This study emphasizes the need for public health education efforts that address the multiple transmission routes for Cryptosporidium and appropriate prevention measures to avoid future transmission.

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Corresponding author
*Author for correspondence: A. L. Valderrama, Ph.D., R.N., National Center for Chronic Disease Prevention and Health Promotion, 4770 Buford Hwy, NE, Atlanta, GA 30341, MS K-47. (Email: AValderrama@cdc.gov)
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11. BG Blackburn , Cryptosporidiosis associated with ozonated apple cider. Emerging Infectious Diseases 2006; 12: 684686.

13. ES Quiroz , An outbreak of cryptosporidiosis linked to a foodhandler. Journal of Infectious Diseases 2000; 181: 695700.

16. G Turabelidze , Communitywide outbreak of cryptosporidiosis in rural Missouri associated with attendance at child care centers. Archives of Pediatrics and Adolescent Medicine 2007; 161: 878883.

20. L Xiao , Identification of 5 types of Cryptosporidium parasites in children in Lima, Peru. Journal of Infectious Diseases 2001; 183: 492497.

22. TF Jones . Changing challenges of bacterial enteric infection in the United States. Journal of Infectious Diseases 2009; 199: 465466.

28. PR Hunter , Sporadic cryptosporidiosis case-control study with genotyping. Emerging Infectious Diseases 2004; 10: 12411249.

30. SL Roy , Risk factors for sporadic cryptosporidiosis among immunocompetent persons in the United States from 1999 to 2001. Journal of Clinical Microbiology 2004; 42: 29442951.

33. LM Fox , LD Saravolatz . Nitazoxanide: a new thiazolide antiparasitic agent. Clinical Infectious Diseases 2005; 40: 11731180.

34. VR Anderson , MP Curran . Nitazoxanide: a review of its use in the treatment of gastrointestinal infections. Drugs 2007; 67: 19471967.

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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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