Skip to main content
×
×
Home

The proportional frequency of the human and bovine types of tubercle bacilli in human pulmonary tuberculosis in the middle and south of Scotland

  • A. Stanley Griffith (a1)
Extract

1. The types of tubercle bacilli have been determined in the sputum of 515 cases of pulmonary tuberculosis occurring in the middle and south of Scotland.

2. Of the 515 cases 484 were human (476 eugonic and eight dysgonic) and thirty-one were bovine infections.

3. With the exception of the strains from one case (case 28) all the bovine strains, seventy in number, were typical culturally and fully virulent for rabbits.

4. The attenuated strains, two in number, from case 28 were slightly less virulent than typical bovine strains for rabbits and (one strain) for guinea-pigs.

5. The percentage of bovine infections found in this series, including the Cumberland case, during the years 1931–9 was 6·0, but excluding that case it was 5·8.

6. The percentage of bovine infections found by Munro during about the same period and covering the same regions was 5·0%.

7. In Munro's series strains of bovine tubercle bacilli were obtained from fifty-eight out of 1165 persons (5·0%). Five of his cases yielded attenuated bovine strains and in one of these the pulmonary tuberculosis was preceded by tuberculosis of the thoracic spine.

8. In my series the attenuated tubercle bacilli came from a case (case 28) of pulmonary tuberculosis which was preceded nearly 20 years previously by tuberculosis of the lower dorsal spine.

Dr Munro and others have made post-mortem examinations on cases of phthisis pulmonalis due to bovine bacilli, but I wish to defer reference to these until we can review them altogether.

In this series there are seven instances of cervical gland enlargement and one instance (case 28) of spinal tuberculosis occurring previous to the development of phthisis pulmonalis. These, I think, are examples of alimentary infection with the bovine tubercle bacillus. Thus, with the three autopsies previously mentioned, there are eleven cases, or about one-third, which are almost certainly alimentary in origin. As for the rest of the cases, 20 in number, no glandular enlargements in neck or abdomen were detected but the majority, if not all, were probably alimentary in origin, since all the persons drank a lot of raw milk and only five came into direct contact with cattle in their employment.

Copyright
References
Hide All
Cobbett, L. (1907). The relations of human and animal tuberculosis. Roy. Comm. on Tuberc. App. 2nd Int. Rep.
Griffith, A. S. (1911). The relations of human and animal tuberculosis. Roy. Comm. on Tuberc. App. Fin. Rep. 1.
Griffith, A. S. (1914). Further investigations of the types of tubercle bacilli occurring in the sputum of phthisical persons. Brit. med. J. 1, 1171.
Griffith, A. S. & Munro, W. T. (1933). Phthisis pulmonalis due to the bovine type of tubercle bacillus. Lancet, 1, 399.
Griffith, A. S. & Munro, W. T. (1935). Family tuberculosis due to bovine tubercle bacilli. Brit. med. J. 2, 147.
Griffith, A. S. & Smith, J. (1938). Bovine phthisis, its incidence in north-east Scotland. Lancet, 1, 739.
Koch, R. (1908). The Relation of Human and Bovine Tuberculosis. International Congress on Tuberculosis, Washington.
Leighton, G. & McKinlay, P. L. (1934). Milk Consumption in Scotland. Department of Health for Scotland.
Munro, W. T. (1939). Epidemiological aspects of pulmonary tuberculosis due to bovine type tubercle bacilli. Trans. Tuberc. Soc. Scot. 27.
Munro, W. T. (1940). 21st Ann. Rep. Fife and Kinross Joint Sanatorium Board.
Munro, W. T. & Cummlng, W. M. (1926). The virulence of tuberculous viruses. Edin. med. J. 33, 97.
Wang, C. Y. (1916). Isolation of tubercle bacilli from sputum and determination of their type. J. Path. Bact. 21, 14.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 5 *
Loading metrics...

Abstract views

Total abstract views: 39 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 13th June 2018. This data will be updated every 24 hours.