Hostname: page-component-76fb5796d-r6qrq Total loading time: 0 Render date: 2024-04-25T08:35:06.117Z Has data issue: false hasContentIssue false

The sub-type classification of strains of foot-and-mouth disease virus

Published online by Cambridge University Press:  15 May 2009

A. J. Forman
Affiliation:
Animal Virus Research Institute, Pirbright, Woking, Surrey, England*
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Sixteen foot-and-mouth disease virus (FMDV) strains of type SAT 1 were compared in complement-fixation tests. With the test used, the range of antigenic variation within a type appeared to be greater than previously described. The concept of a sub-type group within which all strains are more closely related to each other than to any strain outside the group was not supported. Considering the group of strains studied, it is suggested that the classification of strains is best achieved by nominating a reference strain for each sub-type. Others are classified as related strains in one or more sub-type groups according to their relationships with the reference strains.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1975

References

REFERENCES

Brooksby, J. B. (1952). The technique of complement fixation in foot-and-mouth disease research. Agricultural Research Council Report Series No. 12. London: H.M. Stationery Office.Google Scholar
Brooksby, J. B. (1968). Variants and immunity; definitions for serological investigation. International Symposium on Foot-and-Mouth Disease: Variants and Immunity, Lyon 1967. Symposium Series in Immunobiological Standardisation 8, 110. Basel: Karger.Google Scholar
Brown, F. & Cartwright, B. (1963). Purification of radioactive foot-and-mouth disease virus. Nature, London 199, 1168–70.CrossRefGoogle ScholarPubMed
Cowan, K. M. (1968). Immunochemical studies of foot-and-mouth disease. IV. Preparation and evaluation of antisera specific for virus, virus protein sub-unit and the infection-associated antigen. Journal of Immunology 101, 1183–91.CrossRefGoogle ScholarPubMed
Forman, A. J. (1974 a). A study of foot-and-mouth disease virus strains by complement fixation. II. A model for the fixation of complement by antigen/antibody mixtures. Journal of Hygiene 72, 397405.CrossRefGoogle Scholar
Forman, A. J. (1974 b). A study of foot-and-mouth disease virus strains by complement fixation. II. A comparison of tube and microplate tests for the differentiation of strains. Journal of Hygiene 72, 407–13.CrossRefGoogle Scholar
Stellman, C., Moreau, Y. & Favre, H. (1972). System for an early identification of foot-and-mouth disease virus strains. Archiv für die gesamte Virusforschung 37, 351–6.CrossRefGoogle Scholar
Stellman, C., Moreau, Y. & Roumiantzeff, M. (1972). Biomathematical system of relationship and dominance for the classification of foot-and-mouth disease virus strains. Archiv für die gesamte Virusforschung 37, 357–64.CrossRefGoogle Scholar
Traub, E. & Möhlmann, H. (1946). Untersuchungen über immunologische Varianten der Typen A und B des Maul-und Klauenseuchenvirus. Berliner und Münchener Tierärztliche Wochenschrift 1, 15.Google Scholar