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The epidemiology and molecular characterization of methicillin-resistant staphylococci sampled from a healthy Jordanian population

  • A. G. AL-BAKRI (a1), H. AL-HADITHI (a1), V. KASABRI (a2), G. OTHMAN (a1), A. KRIEGESKORTE (a3) and K. BECKER (a3)
  • DOI: http://dx.doi.org/10.1017/S0950268813000010
  • Published online: 23 January 2013
Abstract
SUMMARY

The prevalence of natural carriage and molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci (MR-CoNS) isolates in a Jordanian community were investigated. The MRSA nasal carriage rate in 227 healthy volunteers was 7·5% and the majority (81%) of MRSA harboured the resistance element SCCmec type IVe and were of a novel spa type t9519 (76%); other significant spa gene types were t223 (14·7%) and t044 (5·9%). All MRSA isolates were susceptible to other classes of antibiotics, and tested positive for at least three virulence factor encoding genes, but only two harboured the pvl gene. MR-CoNS carriage was 54·2% and these isolates were characterized by single, double and untypable SCCmec elements, with Staphylococcus epidermidis SCCmec type IVa predominating. Of eight subjects with nasal co-colonization of MR-CoNS + MRSA, three shared SCCmec type IV in both groups of organisms. This is the first report of methicillin-resistant staphylococci carriage in a Jordanian community and its findings are important for epidemiological study and infection control measures of these organisms.

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Corresponding author
*Author for correspondence: Dr A. G. Al-Bakri, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, The University of Jordan, Amman-Jordan. (Email: agbakri@ju.edu.jo)
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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