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Model of therapeutic intervention in anorexia nervosa of adolescents with depressive behavioral disorders

Published online by Cambridge University Press:  13 August 2021

I. Mykhailova ,
D. Mitelov ,
T. Matkovska  and
O. Mayorov
I. Mykhailova*
Affiliation:
Medical, Kharkiv National Medical University, Kharkiv, Ukraine Psychiatry, State Institution “Institute of the Health Care of Children and Adolescents of NAMS of Ukraine”, Kharkiv, Ukraine
D. Mitelov
Affiliation:
Psychiatry, State Institution “Institute of the Health Care of Children and Adolescents of NAMS of Ukraine”, Kharkiv, Ukraine
T. Matkovska
Affiliation:
Psychiatry, State Institution “Institute of the Health Care of Children and Adolescents of NAMS of Ukraine”, Kharkiv, Ukraine
O. Mayorov
Affiliation:
Clinical Informatics And Information Technology In Health Care Management, Kharkiv Medical Academy of Postgraduate Education of the Ministry of Health of Ukraine, Kharkiv, Ukraine
*
*Corresponding author.

Abstract

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Introduction

Anorexia nervosa is often associated with the development of depressive disorders.

Objectives

Skillful dissimulation of the true causes of fasting in adolescents leads to diagnostic errors and delayed adequate therapy.

Methods

The study design includes clinical psychopathological, somatic-neurological, and psychological methods for examination of 54 adolescent girls aged 12-14, with a recurrent depression, and factors determine disorders in alimentary behavior (anorexia nervosa) in teen-agers. The following psychological tests were performed: Children’s Depression Rating Scale Revised, Columbia - Suicide Severity Rating Scale, Mendelevitch - Yakhin Scale to establish a neurotic state.

Results

in all adolescent girls with anorexia nervosa depressive disorders were present in prepuberty. Behavioral syndrome and aggressive vulnerability prevailed in the structure of depression. Cognitive component was represented in the form of unstable type of poor memory and decreased rate of sensorimotor reactions with episodic recurrent attacks of bulimia. Our model of therapeutic intervention included: behavioral intervention, intravenous administration of Cerebrolysin 10,0 with 0,9 % Sodium chloride 200,0 (No.15). Therapeutic neuroplasticity, multimodal effect, and a disease - modifying therapy effects in short terms provide regression of emotional-cognitivity.

Conclusions

In adolescent girls with a recurrent depression anorexia nervosa has specific features that require early differentiation, neurotropic and neurodegenerative therapy.

Keywords

depressionadolescentbehavioral disordersanorexia nervosa
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S225
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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