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MECHANICAL HEART VALVES AND PREGNANCY

  • CYNTHIA MAXWELL (a1) and MATHEW SERMER (a1)
Abstract

Mechanical heart valves pose a particular challenge in pregnancy, as the primary agent used to prevent valve thrombosis, coumadin (warfarin), is a known teratogen. Alternatives to coumadin, such as unfractionated heparin (UFH) and low-molecular weight heparin (LMWH) are safer for the fetus, particularly during the first trimester of pregnancy, but expose the mother to potential valve failure. This review will examine these controversies and the complex literature regarding management in pregnancy.

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Corresponding author
Cynthia Maxwell, Mount Sinai Hospital, Department of Obstetrics and Gynaecology, 600 University Avenue, Toronto ON, M5G 1X5Canada.
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Fetal and Maternal Medicine Review
  • ISSN: 0965-5395
  • EISSN: 1469-5065
  • URL: /core/journals/fetal-and-maternal-medicine-review
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