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The collective nature of personalized medicine

  • IAN VINCENT MCGONIGLE (a1) (a2)
Abstract
Summary

Precision medicine, incorporating personalized medicine, is an emerging medical model that holds great promise for improving the prevention, diagnosis and treatment of many diseases. The future success of precision medicine, however, depends on the establishment of large databases that collate diverse data, including family genealogies, disease histories, drug sensitivities and genomic data. Herein I raise some of the social and ethical challenges that such a system faces, specifically: the enrolment of volunteers into large genetic databases; the need for a change in mindset of clinicians, patients and the wider public; and the need for interdisciplinary ethics considering the emerging issues. Finally I argue that the future potential of ‘personalized’ medicine crucially depends on ‘collective’ participation of informed citizens.

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*Corresponding author: Tel: +972 54 935 1211. E-mail: mcgonigle@fas.harvard.edu
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

J. Dumit (2012). Drugs for Life: How Pharmaceutical Companies Define Our Health (Experimental Futures). Durham, NC, USA: Duke University Press.

D. Gurwitz (2015). Genetic privacy: trust is not enough. Science 347(6225), 957958.

V. Marx (2015). The DNA of a nation. Nature 524(7566), 503505.

B. Prainsack (2014 b). Personhood and solidarity: what kind of personalized medicine do we want? Personalized Medicine 11(7), 651657.

KS. Rajan (2006). Biocapital: the Constitution of Postgenomic Life. Durham, NC, USA: Duke University Press.

N. Shomron (2014). Prioritizing personalized medicine. Genetics Research 96, e007.

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Genetics Research
  • ISSN: 0016-6723
  • EISSN: 1469-5073
  • URL: /core/journals/genetics-research
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