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Further evidence for the importance of parental source of the Xce allele in X chromosome inactivation

  • Deborah J. Fowlis (a1), John D. Ansell (a1) and H. Spedding Micklem (a1)
Summary
Summary

Using mice that were mosaics for both Xce and phosphoglycerate kinase (Pgk-1) alleles, we present further evidence that the parental source of the X chromosome may affect the probability of that X chromosome remaining active. The reciprocal cross differences in PGK-1 activity described here are intermediate between those published previously for other alleles of Xce.

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Ansell J. D. & Micklem H. S. (1986). Genetic markers for following cell populations. Handbook of Experimental Immunology (ed. Weir D. M.), vol. 2, 4th edn, ch. 56, Blackwell Scientific Publications, Oxford, London, Edinburgh.
Bucher T. & Krietsch W. P. G. (1988). Glycolytic enzymes in genetic research. Advances in Clinical Enzymology 6, 3547.
Cattanach B. M. (1975). Control of X chromosome inactivation. Annual Review of Genetics 9, 118.
Cattanach B. M. & Isaacson J. H. (1967). Controlling elements in the mouse. X chromosome. genetics 57, 331346.
Cattanach B. M. & Papworth D. (1981). Controlling elements in the mouse V. Linkage tests with X-linked genes. Genetical Research 38, 5770.
Cattanach B. M., Perez J. N. & Pollard C. E. (1970). Controlling elements in the mouse X chromosome. II. Location in the linkage map. Genetical Research 15, 183195.
Cattanach B. M., Pollard C. E. & Perez J. N. (1969). Controlling elements in the mouse X chromosome. I. Interaction with the X-linked genes. Genetical Research 14, 223235.
Evans H. J., Ford C. E., Lyon M. F. & Gray J. (1965). DNA replication and genetic expression in female mice with morphologically distinguishable X chromosomes. Nature 206, 900903.
Falconer D. S., Isaacson J. H. & Gauld I. K. (1982). Non-random X chromosome expression in the mouse: difference of reaction to imprinting. Genetical Research 39, 237259.
Fialkow P. J., Lisker R., Giblett E. R. & Zavala C. (1970). Xg locus: failure to detect inactivation in females with chonic myelocytic leukaemia. Nature 226, 367368.
Forrester L. M. & Ansell J. D. (1985). Parental influences on X chromosome expression. Genetical Research 45, 95100.
Frels W. I., Rossant J. & Chapman V. M. (1979). Maternal X chromosome expression in mouse chorionic ectoderm. Developmental Genetics 1, 123132.
Green M. C. (1981). Genetic Variants and Strains of the Laboratory Mouse. Gustav Fischer Verlag, Stuttgart, New York.
Johnston P. G. & Cattanach B. M. (1981). Controlling elements in the mouse. IV. Evidence of non-random X-inactivation. Genetical Research 37, 151160.
Kahan B. & DeMars R. (1975). Localized depression on the human inactive X-chromosome in mouse-human cell hybrids. Proceedings of the National Academy of Sciences, USA 72, 15101514.
Krietsch W. K. G., Fehlau M., Renner P., Bucher T. & Fundele R. (1986). Expression of X-linked phosphoglycerate kinase in early mouse embryos homozygous at the Xce locus. Differentiation 31, 5054.
Lyon M. F. (1962). Sex chromatin and gene action in the mammalian X-chromosome. American Journal of Human Genetics 14, 135148.
Migeon B. R. (1972). Stability of X-chromosomal inactivation in human somatic cells. Nature 239, 8789.
Migeon B. R., Shapiro L. J., Norum R. A., Mohandas T., Axelman J. & Dabova R. L. (1982). Differential expression of steroid sulphatase locus on action and inactive human X chromosome. Nature 299, 838840.
Mukherjee B. B., Mukherjee A. B. & Mukherjee A. B. (1970). Is inactivation of the X chromosome in the female mule random? Nature 228, 13211322.
Nielsen J. T. & Chapman V. M. (1977). Electrophoretic variation for X-chromosome-linked phosphoglycerate kinase (PGK-1) in the mouse. Genetics 87, 319325.
Papaioannou V. E. & West J. D. (1981). Relationship between the parental origin of the X chromosomes, embryonic cell lineage and X chromosome expression in mice. Genetical Research 37, 183197.
Rastan S. & Cattanach B. M. (1983). Interaction between the Xce locus and paternal imprinting of the X chromosome in mouse yolk sac endoderm. Nature 303, 635636.
Shapiro L. J., Mohandas T., Weiss R. & Romeo G. (1979). Non-inactivation of X-chromosome locus in man. Science 204, 12241226.
Takagi N. & Sasaki M. (1975). Preferential inactivation of the paternally derived X chromosome in the extra-embryonic membranes of the mouse. Nature 256, 640642.
West J. D., Freis W. I., Chapman V. M. & Papaioannou V. E. (1977). Preferential expression of the maternally derived X-chromosome in the mouse yolk sac. Cell 12, 873882.
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Genetics Research
  • ISSN: 0016-6723
  • EISSN: 1469-5073
  • URL: /core/journals/genetics-research
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