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Map position of dysgenetic lens (dyl) locus on chromosome 4 in the mouse

  • S. Sanyal (a1), R. van Nie (a2), J. de Moes (a2) and R. K. Hawkins (a1)
Summary

The autosomal recessive gene, dysgenetic lens (dyl) in the mouse has been mapped on chromosome 4. Two- and three-point crosses involving b (brown) and Mup-1 (Major urinary protein-1) indicate the following gene order: dyl–b–Mup-1. The approximate distance between dyl and b is 12 and between dyl and Mup-1 is 20 cM.

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References
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Green, E. L. (1966). Breeding systems, In Biology of the Laboratory Mouse (ed. Green, E. L.), pp. 1122. New York: McGraw-Hill.
Green, M. C. (1963). Methods for testing linkage. In Methodology in Mammalian Genetics (ed. Burdette, W. J.), pp. 5682. San Francisco: Golden-Day.
Mouse News Letter (1985), no. 73, pp. 68.
Sanyal, S. & Bal, A. K. (1973). Comparative light and electron microscopic study of retinal histogenesis in normal and rd mutant mice. Zeitschrift für Anatomie und Entwicklungsgeschichte 142, 219239.
Sanyal, S. & Hawkins, R. K. (1979). Dysgenetic lens – a new gene in the mouse. Investigative Ophthalmology and Visual Science 18, 642645.
Wilcox, F. H. (1975). Simplified procedure for electrophoresis of the major urinary protein complex of Mus musculus. Biochemical Genetics 13, 243245.
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Genetics Research
  • ISSN: 0016-6723
  • EISSN: 1469-5073
  • URL: /core/journals/genetics-research
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