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Successful Eradication of a Monoclonal Strain of Klebsiella pneumoniae during a K. pneumoniae Carbapenemase-Producing K. pneumoniae Outbreak in a Surgical Intensive Care Unit in Miami, Florida

Published online by Cambridge University Press:  02 January 2015

L. Silvia Munoz-Price*
Affiliation:
Division of Infectious Diseases, Department of Medicine, Miami, Florida University of Miami, and Jackson Memorial Hospital, Miami, Florida
Carolina De La Cuesta
Affiliation:
Division of Infectious Diseases, Department of Medicine, Miami, Florida University of Miami, and Jackson Memorial Hospital, Miami, Florida
Stephen Adams
Affiliation:
University of Miami, and Jackson Memorial Hospital, Miami, Florida
Mary Wyckoff
Affiliation:
Department of Surgery, Miami, Florida University of Miami, and Jackson Memorial Hospital, Miami, Florida
Timothy Cleary
Affiliation:
Department of Pathology, Miami, Florida
Sandra P. McCurdy
Affiliation:
Pfizer Global Research and Development, Groton, Connecticut, Rush University Medical Center, Chicago, Illinois
Michael D. Huband
Affiliation:
Pfizer Global Research and Development, Groton, Connecticut, Rush University Medical Center, Chicago, Illinois
M. Megan Lemmon
Affiliation:
Pfizer Global Research and Development, Groton, Connecticut, Rush University Medical Center, Chicago, Illinois
MaryKay Lescoe
Affiliation:
Pfizer Global Research and Development, Groton, Connecticut, Rush University Medical Center, Chicago, Illinois
Fadia B. Dibhajj
Affiliation:
Pfizer Global Research and Development, Groton, Connecticut, Rush University Medical Center, Chicago, Illinois
Mary K. Hayden
Affiliation:
Department of Pathology, Rush University Medical Center, Chicago, Illinois Section of Infectious Diseases, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois
Karen Lolans
Affiliation:
Department of Pathology, Rush University Medical Center, Chicago, Illinois
John P. Quinn
Affiliation:
Pfizer Global Research and Development, Groton, Connecticut, Rush University Medical Center, Chicago, Illinois
*
Jackson Memorial Hospital, Park Plaza West L-302, 1611 NW 12th Avenue, Miami, FL 33136-1096, (smunozprice@med.miami.edu)

Extract

We describe the investigation and control of a Klebsiella pneumoniae carbapenemase-producing K. pneumoniae outbreak in a 20-bed surgical intensive care unit during the period from January 1, 2009 through January 1, 2010. Nine patients were either colonized or infected with a monoclonal strain of K. pneumoniae. The implementation of a bundle of interventions on July 2009 successfully controlled the further horizontal spread of this organism.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2010

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References

1.Nordmann, P, Cuzon, G, Naas, T. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis 2009;9:228236.CrossRefGoogle ScholarPubMed
2.Patel, G, Huprikar, S, Factor, SH, Jenkins, SG, Calfee, DP. Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infect Control Hosp Epidemiol 2008;29:10991106.CrossRefGoogle ScholarPubMed
3.Gasink, LB, Edelstein, PH, Lautenbach, E, Synnestvedt, M, Fishman, NO. Risk factors and clinical impact of Klebsiella pneumoniae carbapenemaseproducing K. pneumoniae. Infect Control Hosp Epidemid 2009;30:11801185.CrossRefGoogle Scholar
4.Clinical Laboratory Standards Institute (CLSI). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard. CLSI document M07-A8. 8th ed. Wayne, PA: CLSI; 2009.Google Scholar
5.Clinical Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing: 19th informational supplement. CLSI document M100-S19. Wayne, PA: CLSI; 2009.Google Scholar
6.Tenover, FC, Arbeit, RD, Goering, RV, et al.Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995;33:22332239.Google ScholarPubMed
7.Lolans, K, Calvert, K, Won, S, Clark, J, Hayden, MK. Direct ertapenem disk screening method for identification of KPC-producing Klebsiella pneumoniae and Escherichia coli in surveillance swab specimens. J Clin Microbiol 2010;48:836841.CrossRefGoogle ScholarPubMed
8.Kochar, S, Sheard, T, Sharma, R, et al. Success of an infection control program to reduce the spread of carbapenem-resistant Klebsiella pneumoniae. Infect Control Hosp Epidemiol 2009;30:447452.CrossRefGoogle ScholarPubMed
9.Munoz-Price, LS, Hayden, MK, Lolans, K, et al.Successful control of an outbreak of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae at a long-term acute care hospital. Infect Control Hosp Epidemiol 2010;31:341347.CrossRefGoogle Scholar
10. Centers for Disease Control and Prevention (CDC). Guidance for control of infections with carbapenem-resistant or carbapenemase-producing En-terobacteriaceae in acute care facilities. MMWR Morb Mortal Wkly Rep 2009;58:256260.Google ScholarPubMed
11.Leavitt, A, Navon-Venezia, S, Chmelnitsky, I, Schwaber, MJ, Carmeli, Y. Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital. Antimicrob Agents Chemother 2007;51:30263029.CrossRefGoogle Scholar
12.Bratu, S, Landman, D, Haag, R, et al.Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City: a new threat to our antibiotic armamentarium. Arch Intern Med 2005;165:14301435.CrossRefGoogle ScholarPubMed
13.Munoz-Price, LS, Quinn, JP. The spread of Klebsiella pneumoniae car-bapenemases: a tale of strains, plasmids, and transposons. Clin Infect Dis 2009;49:17391741.CrossRefGoogle ScholarPubMed
14.Srinivasan, A, Patel, JB. Klebsiella pneumoniae carbapenemase-producing organisms: an ounce of prevention really is worth a pound of cure. Infect Control Hosp Epidemiol 2008;29:11071109.CrossRefGoogle Scholar
15. Research Committee of the Society of Healthcare Epidemiology of America. SHEA position paper. Enhancing patient safety by reducing healthcare-associated infections: the role of discovery and dissemination. Infect Control Hosp Epidemiol 2010;31:118123.CrossRefGoogle Scholar
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Successful Eradication of a Monoclonal Strain of Klebsiella pneumoniae during a K. pneumoniae Carbapenemase-Producing K. pneumoniae Outbreak in a Surgical Intensive Care Unit in Miami, Florida
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Successful Eradication of a Monoclonal Strain of Klebsiella pneumoniae during a K. pneumoniae Carbapenemase-Producing K. pneumoniae Outbreak in a Surgical Intensive Care Unit in Miami, Florida
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