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Antimicrobial Use Prior to the Acquisition of Multiresistant Bacteria

  • Matthieu Eveillard (a1), Jean-Luc Schmit (a2) and François Eb (a1)


We assessed whether patients who acquired methicillin-resistant Staphylococcus aureus (MRSA) had less exposure to antimicrobial agents than did those who acquired Enterobacteriaceae that produced extended-spectrum β-lactamase (ESβL). In a 6-month, prospective study, ESβL carriers had received antimicrobial therapy more often than had MRSA carriers. Amoxicillin-clavulanic acid, fluoroquinolones, and third-generation cephalosporins, especially ceftazidime, had been prescribed more often for ESβL carriers than for MRSA carriers.


Corresponding author

Unité d'Hygiène el de Prévention des Infections Nosocomiales, Centre Hospitalier Universitaire d'Amiens, Hôpital Nord, 80054 Amiens Cedex 1, France


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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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