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Around-the-Clock, Rapid Diagnosis of Influenza by Means of Membrane Chromatography Antigen Testing Confirmed by Polymerase Chain Reaction

Published online by Cambridge University Press:  02 January 2015

Anna C. Nilsson ,
Birgitta Alemo ,
Per Björkman ,
Lena Dillner ,
Åsa Melhus ,
Berit Nilsson  and
Anders Widell
Anna C. Nilsson
Affiliation:
Department of Clinical Sciences, Malmö Infectious Disease Research Unit, Malmö University Hospital, Lund University, Malmö
Birgitta Alemo
Affiliation:
Department of Clinical Chemistry, Malmö University Hospital, Lund University, Malmö
Per Björkman
Affiliation:
Department of Clinical Sciences, Malmö Infectious Disease Research Unit, Malmö University Hospital, Lund University, Malmö
Lena Dillner
Affiliation:
Department of Clinical Microbiology, Malmö University Hospital, Lund University, Malmö
Åsa Melhus
Affiliation:
Department of Clinical Microbiology, Uppsala University Hospital, Uppsala, Sweden
Berit Nilsson
Affiliation:
Department of Clinical Microbiology, Malmö University Hospital, Lund University, Malmö
Anders Widell*
Affiliation:
Department of Clinical Microbiology, Malmö University Hospital, Lund University, Malmö
*
Department of Clinical Microbiology, Malmö University Hospital, Malmö, Sweden (Anders.Widell@med.lu.se)
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Abstract

One rapid membrane chromatography test and 2 immunofluorescence tests were compared with polymerase chain reaction as tools for the diagnosis of influenza in 277 patients treated in an emergency department. The sensitivity on days 1-3 of symptoms was 71% for the rapid membrane chromatography test, 70% for the first immunofluorescence test, and 79% for the second immunofluorescence test. Rapid tests are useful for round-the-clock identification of influenza, with follow-up polymerase chain reaction used for confirmation.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 29 , Issue 2 , February 2008 , pp. 177 - 179
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

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