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Bacitracin Versus Mupirocin for Staphylococcus aureus Nasal Colonization

  • Norberto E. Soto (a1), Ashok Vaghjimal (a1), Annette Stahl-Avicolli (a2), John R. Protic (a3), Larry I. Lutwick (a1) and Edward K. Chapnick (a1)...
Abstract
Abstract

We performed a randomized prospective study of 5-day treatment with topical mupirocin or bacitracin for the elimination of Staphylococcus aureus nasal colonization in healthcare workers (HCWs). Nasal cultures were obtained from 141 HCWs, 37 (26%) of whom showed S aureus. After 72 to 96 hours of treatment, the organism was eradicated in 15 (94%) of 16 by mupirocin and in 8 (44%) of 18 by bacitracin (P=.0031). Similar efficacy was demonstrated at 30 days. Mupirocin may be more effective than bacitracin for eradication of S aureus in healthy HCWs.

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Maimonides Medical Center, 4802 Tenth Ave, Brooklyn, NY 11219
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3. JW Kluytmans , JW Mouton , MFQ VandenBergh , M-JAAJ Manders , APWM Maat , JHT Wagenvoort , et al. Reduction of surgical-site infections in cardiothoracic surgery by elimination of nasal carriage of Staphylococcus aureus. Infect Control Hosp Epidemiol 1996;17:780785.

4. R Raz , D Mirn , R Colodner Z Staler , Z Samar , Y Keneess . A 1-year trial in the prevention of recurrent staphylococcal nasal colonization and skin infection. Arch Intern Med 1996;156:11091112.

5. MA Miller A Dascal , J Portnoy , J Mendelson . Development of mupirocin resistance among methicillin-resistant Staphylococcus aureus after widespread use of nasal mupirocin ointment Infect Control Hosp -Epidemiol 1996;17:811813.

9. JF Roccaforte , MJ Bittner , CA Stumpf LC Prehelm . Attempts to eradicate methicillin-resistant Staphylococcus aureus colonization with the use of trimethoprim-sulfamethoxazole, rifampin, and bacitracin. Am J Infect Control 1988;16:141146.

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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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