Hostname: page-component-8448b6f56d-t5pn6 Total loading time: 0 Render date: 2024-04-19T13:52:35.312Z Has data issue: false hasContentIssue false

Quantifying Antimicrobial Exposure: Hazards in Populations With End-Stage Renal Disease

Published online by Cambridge University Press:  05 December 2016

Graham M. Snyder*
Affiliation:
Department of Medicine, Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts
Christopher McCoy
Affiliation:
Department of Pharmacy, Beth Israel Deaconess Medical Center, Boston, Massachusetts
Erika M. C. D’Agata
Affiliation:
Department of Medicine, Rhode Island Hospital, Brown University, Providence, Rhode Island
*
Address correspondence to Dr Graham M. Snyder, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Mailstop SL-435, Boston, MA 02215 (gsnyder@bidmc.harvard.edu).

Abstract

Using a rigorously collected data set of antimicrobial use among patients receiving chronic hemodialysis, antimicrobial use was calculated using 3 different methodologies: daily defined dose, days of therapy, and start–stop days. Estimates of antimicrobial use varied by as much as 10-fold, depending on the type of antimicrobial.

Infect Control Hosp Epidemiol 2017;38:360–363

Type
Concise Communications
Copyright
© 2016 by The Society for Healthcare Epidemiology of America. All rights reserved 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Barlam, TF, Cosgrove, SE, Abbo, LM, et al. Implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare qEpidemiology of America. Clin Infect Dis 2016;62:e51e77.Google Scholar
2. WHOCC–ATC/DDD Index. World Health Organization website. http://www.whocc.no/atc_ddd_index/. Published 2011. Accessed July 10, 2012.Google Scholar
3. Polk, RE, Fox, C, Mahoney, A, Letcavage, J, MacDougall, C. Measurement of adult antibacterial drug use in 130 US hospitals: comparison of defined daily dose and days of therapy. Clin Infect Dis 2007;44:664670.Google Scholar
4. Zagorski, BM, Trick, WE, Schwartz, DN, et al. The effect of renal dysfunction on antimicrobial use measurements. Clin Infect Dis 2002;35:14911497.CrossRefGoogle ScholarPubMed
5. Snyder, GM, Patel, PR, Kallen, AJ, Strom, JA, Tucker, JK, D’Agata, EM. Antimicrobial use in outpatient hemodialysis units. Infect Control Hosp Epidemiol 2013;34:349357.Google Scholar
6. Snyder, GM, Patel, PR, Kallen, AJ, Strom, JA, Tucker, JK, D’Agata, EM. Factors associated with the receipt of antimicrobials among chronic hemodialysis patients. Am J Infect Control 2016;44:12691274.Google Scholar
7. Lin, MY, Hota, B, Khan, YM, et al. Quality of traditional surveillance for public reporting of nosocomial bloodstream infection rates. JAMA 2010;304:20352041.Google Scholar