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Risk Factors for Healthcare-Associated, Laboratory-Confirmed Influenza in Hospitalized Pediatric Patients: A Case-Control Study

  • Kateri H. Leckerman (a1), Eileen Sherman (a2), Jillian Knorr (a2), Theoklis E. Zaoutis (a1) (a3) (a4) and Susan E. Coffin (a1) (a2) (a3) (a4)...

We conducted a case-control study of 46 hospitalized pediatric patients with healthcare-associated laboratory-confirmed influenza (HA-LCI). We sought to determine the characteristics and outcomes of children with HA-LGI and to identify risk factors for HA-LCI. Although we failed to identify any differences in clinical exposures during the 3 days prior to onset of HA-LCI, multivariate analysis showed that asthma was an independent risk factor for HA-LCI (odds ratio, 3.49 [95% confidence interval, 1.25–9.75]).

Corresponding author
Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104 (
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1.S Weingarten , M Friedlander , D Rascon , M Ault , M Morgan , RD Meyer . Influenza surveillance in an acute-care hospital. Arch Intern Med 1988;148:113116.

7.FM Blachere , WG Lindsley , TA Pearce , et al.Measurement of airborne influenza virus in a hospital emergency department. Clin Infect Dis 2009;48(4:438440.

8.JR Serwint , RM Miller . Why diagnose influenza infections in hospitalized pediatric patients? Pediatr Infect Dis J 1993;12(3:200204.

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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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