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Efficacy of a Novel Light-Activated Antimicrobial Coating for Disinfecting Hospital Surfaces

  • Salim Ismail (a1), Stefano Perni (a1), Jonathan Pratten (a1), Ivan Parkin (a2) and Michael Wilson (a1)...
Abstract

Silicone polymers containing the light-activated antimicrobial agent methylene blue with or without gold nanoparticles were evaluated for their ability to reduce the microbial load on surfaces in a clinical environment. When irradiated with white light, polymers containing nanogold were more effective in this respect than those containing only methylene blue.

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Corresponding author
Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, 256 Gray's Inn Road, London WCIX 8LD, United Kingdom (mike.wilson@ucl.ac.uk)
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1. V Decraene , J Pratten , M Wilson . Cellulose acetate containing toluidine blue and rose bengal is an effective antimicrobial coating when exposed to white light. Appl Environ Microbiol 2006;72:44364439.

2. S Perni , C Piccirillo , J Pratten , et al. The antimicrobial properties of light-activated polymers containing methylene blue and gold nanoparticles. Biomaterials 2009;30:8993.

4. S Murchan , H Aucken , GL O'Neill , et al. Emergence, spread, and characterization of phage variants of epidemic methicillin-resistant Staphylococcus aureus 16 in England and Wales. J Clin Microbiol 2004;42:51545160.

6. MN Usacheva , MC Teichert , MA Biel . Comparison of the methylene blue and toluidine blue photobactericidal efficacy against gram-positive and gram-negative microorganisms. Lasers Surg Med 2001;29:165173.

7. V Decraene , J Pratten , M Wilson . Novel light-activated antimicrobial coatings are effective against surface-deposited Staphylococcus aureus. Curr Microbiol 2008;57:269273.

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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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