Skip to main content Accessibility help

Implementation of an Antimicrobial Stewardship Program at a 60-Bed Long-Term Acute Care Hospital

  • Perry G. Pate (a1), Donald F. Storey (a1) and Donna L. Baum (a2)


We implemented an antimicrobial stewardship program at an urban, 60-bed long-term acute care hospital using a strategy of weekly postprescriptive chart audit with intervention and feedback. The results for the first 15 months demonstrated 80% acceptance of recommendations, a 21% reduction in use, and a 28% reduction in cost per patient-day.


Corresponding author

5939 Harry Hines Boulevard, Suite 845, Dallas, TX 75235 (


Hide All

P.G.P. and D.ES. contributed equally to this article



Hide All
1. Medicare Payment Advisory Commission. Report to the Congress: Medicare Payment Policy Report. March 2011. Accessed August 26, 2011.
2. Gould, CV, Rothenberg, R, Steinberg, J. Antibiotic resistance in long-term acute care hospitals: the perfect storm. Infect Control Hosp Epidemiol 2006;27:920925.
3. Weinstein, RA, Munoz-Price, LS. Long-term acute care hospitals. Clin Infect Dis 2009;49:438443.
4. Goldstein, EJ, Polonsky, J, Touzani, M, Citron, DM. C. difficile infection (CDI) in a long-term acute care facility (LTAC). Anaerobe 2009;15:241243.
5. Bonilla, H, Huband, MD, Seidel, J, et al. Multicity outbreak of linezolid-resistant Staphylococcus epidermidis associated with clonal spread of a c/r-containing strain. Clin Infect Dis 2010;51:796800.
6. Jump, RL, Riggs, MM, Sethi, AK, et al. Multihospital outbreak of Clostridium difficile infection, Cleveland, Ohio, USA. Emerg Infect Dis 2010;16:827829.
7. Won, SY, Munoz-Price, LS, Lolans, K, Hota, B, Weinstein, RA, Hayden, MK. Emergence and rapid regional spread of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae. Clin Infect Dis 2011;53:532540.
8. Kravitz, GR, Glynn, PF, Bornstein, PF, Eirtz, JJ, Krason, DA, Kahn, MA. Implementation of an antibiotic stewardship program (ASP) at a long-term acute care hospital (LTACH): fertile ground. In: Program and Abstracts of the 19th Annual Scientific Meeting of the Society for Healthcare Epidemiology of America. San Diego: March 18-22, 2009. Abstract 72.
9. National Healthcare Safety Network. Multidrug-Resistant Organism and Clostridium difficile Infection (MDRO/CDI) Module . June 2011. Accessed September 4, 2011.
10. Cohen, SH, Gerding, DN, Johnson, S, et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect Control Hosp Epidemiol 2010;31:431455.


Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed