Skip to main content

Microbiological Evaluation of Central Venous Catheter Administration Hubs

  • Jean-Christophe Lucet (a1), Jan Hayon (a2), Fabrice Bruneel (a3), Jean-Louis Dumoulin (a4) and Marie-Laure Joly-Guillou (a5)...

We compared, in three intensive care units, colonization of hubs with hub protection boxes or hubs with needleless closed connectors; 137 central venous catheters and 451 hubs were randomized in two groups with similar characteristics. Catheter and hub colonization were not different between the two groups. Among 30 colonized catheters, the same isolate was found in only two hubs; hub contamination rarely is responsible for catheter colonization in short-term catheters. Further studies are required to evaluate the benefit of protected hubs compared with unprotected hubs.

Corresponding author
UHLIN, Groupe Hospitalier Bichat-Claude Bernard, 46 rue Henri Huchard, 75877 Paris, Cedex 18, France
Hide All
1.Widmer, AF. Intravenous-related infections. In: Wenzel, RP, ed. Prevention and Control of Nosocomial Infections. 3rd ed. Baltimore, MD: Williams & Wilkins; 1997:771805.
2.Pearson, ML, the Hospital Infections Control Practices Advisory Committee. Guideline for prevention of intravascular device-related infections. Infect Control Hosp Epidemiol 1996;17:438473.
3.Brun-Buisson, C, Abrouk, F, Legrand, P, Huet, Y, Larabi, S, Rapin, M. Diagnosis of central venous catheter-related sepsis. Critical level of quantitative tip cultures. Arch Intern Med 1987;147:873877.
4.Maki, DG, Ringer, M. Evaluation of dressing regimens for prevention of infection with peripheral intravenous catheter. JAMA 1987;258:23972403.
5.Arduino, MJ, Bland, LA, Danzig, LE, McAllister, SK, Aguero, SM. Microbiologic evaluation of needleless and needle-access devices. Am J Infect Control 1997;25:377380.
6.Luebke, MA, Arduino, MJ, Duda, DL, Dudar, TE, McAllister, SK, Bland, IA, et al. Comparison of the microbial barrier properties of a needleless and conventional needle-based intravenous access system. Am J Infect Control 1998;26:437441.
7.Adams, KS, Zehrer, CL, Thomas, W. Comparison of a needleless system with conventional heparin locks. Am J Infect Control 1993;21:263269.
8.Crow, S, Conrad, SA, Chaney-Rowell, C, King, JW. Microbial contamination of arterial infusions used for hemodynamic monitoring: a randomized trial of contamination with sampling through conventional stopcocks versus a novel closed system. Infect Control Hosp Epidemiol 1989;10:557561.
9.Danzig, LE, Short, LJ, Coffings, K, Mahoney, M, Sepe, S, Bland, L, et al. Bloodstream infections associated with a needleless intravenous infusion system in patients receiving home infusion therapy. JAMA 1995;273:18621864.
10.Raad, I, Abi-Said, D, Awad, A, et al. Optimal frequency of changing intravenous administration sets: is it safe to prolong duration of use beyond 3 days? In: Proceedings of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 28-October 1, 1997; Toronto, Ontario, Canada. Abstract J-199:325.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *


Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 2 *
Loading metrics...

Abstract views

Total abstract views: 80 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 23rd September 2018. This data will be updated every 24 hours.