Skip to main content Accessibility help
×
×
Home

Multiresistant Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Causing an Outbreak of Nosocomial Bloodstream Infection

  • Artemio Gonzalez-Vertiz (a1), Dolores Alcantar-Curiel (a2), Marcela Cuauhtli (a1), Carlos Daza (a2), Catalina Gayosso (a2), Graciela Solache (a1), Cruz Horta (a3), Francisco Mejia (a3), Jose I. Santos (a2) and Celia Alpuche-Aranda (a2)...

Abstract

This article describes an outbreak of bloodstream infection due to clonal dissemination of multiresistant Klebsiella pneumoniae in a neonatal area, during August 1999, in México City General Hospital. The intestinal tract was the likely reservoir, and intensification of Contact Precaution measures contained the outbreak.

Copyright

Corresponding author

Experimental Medicine Department, National University of Mexico-Mexico City General Hospital, Dr Balmis 148, 06726 México D.F

References

Hide All
1.Eisenstein, BI, Zaleznic, DF. Enterobacteriaceae. In: Principles and Practice of Infectious Diseases. 5th ed. Sidup, Kent, UK: Churchill Livingstone; 2000:22942310.
2.Jacoby, GA. Extended-spectrum β-lactamases and other enzymes provided resistance to oxyimino-β-lactams. Infect Dis Clin North Am 1997;11:875887.
3.Rice, LB, Willey, SH, Papanicolaou, GA, Medeiros, AA, Eliopoulos, GM, Moellering, RC Jr, et al.Outbreak of ceftazidime resistance caused by extended-spectrum β-lactamases at a Massachusetts chronic-care facility. Antimicrob Agents Chemother 1990;34:21932199.
4.Ríos-Martinez, C, Guerrero-Camacho, A, Machuca-Becerril, O, Miranda-Novales, G, Solorzano-Santos, F, Reyes-Vega, S, et al.Brote por Klebsiella pneumoniae multirresistente en una unidad de cuidados neonatales. Análisis epidemiológico y molecular. In: Program and Abstracts of the 25th Congreso Anual de la Asociación Mexicana de Infectología y Microbiología Clínica; León, Guanajuato, Mexico; June 28-July 1, 2000. Abstract 159.
5.Garner, JS, Jarvis, WR, Emori, TG, Horan, TC, Hughes, JM. CDC definitions for nosocomial infections. In: Olmsted, RN, ed. APIC Infection Control and Applied Epidemiology: Principles and Practices. St. Louis, MO: Mosby; 1996:A1A20.
6.National Committee for Clinical Laboratory Standards 2000. Methods for Dilution Antimicrobial Susceptibility Test for Bacteria That Grow Aerobically. 5th ed. Wayne, PA: National Committee for Clinical Laboratory Standards; 2000.
7.Goering, R. Molecular epidemiology of nosocomial infection: analysis of chromosomal restriction fragment patterns by pulsed-field gel electrophoresis. Infect Control Hosp Epidemiol 1993;14:595600.
8.Miller, JH. Experiments in Molecular Genetics. New York, NY: Cold Spring Harbor Laboratory; 1972:387.
9.Mathew, M, Harris, AM, Marshall, MJ, Ross, GW. The use of analytical isoelectric focusing for detection and identification of β-lactamases. J Gen Microbiol 1975;88:169178.
10.Jarvis, WR. The epidemiology of colonization. Infect Control Hosp Epidemiol 1996;17:4752.
11.Silva, J, Aguilar, C, Ayala, G, Estrada, MA, Garze-Ramos, U, Lara-Lemus, R, et al.TLA-1: a new plasmid-mediated extended-spectrum β-lactamase from Escherichia coli. Antimicrob Agents Chemother 2000;44:9971003.
12.Winokur, PL, Canton, R, Casellas, JM, Legakis, N. Variations in the prevalence of strains expressing an extended spectrum β-lactamase phenotype and characterization of isolates from Europe, the Americas and the Western Pacific Region. Clin Infect Dis 2001;32(suppl 2):S94S103.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed