Skip to main content Accessibility help

Prevalence of and Factors Associated With Multidrug Resistant Organism (MDRO) Colonization in 3 Nursing Homes

  • James A. McKinnell (a1) (a2), Loren G. Miller (a1), Raveena Singh (a3), Ken Kleinman (a4), Ellena M. Peterson (a5), Kaye D. Evans (a5), Tabitha D. Dutciuc (a3), Lauren Heim (a3), Adrijana Gombosev (a3), Marlene Estevez (a3), Bryn Launer (a1), Tom Tjoa (a3), Steven Tam (a3), Michael A. Bolaris (a1) and Susan S. Huang (a3)...


Nursing home residents are at risk for acquiring and transmitting MDROs. A serial point-prevalence study of 605 residents in 3 facilities using random sampling found MDRO colonization in 45% of residents: methicillin-resistant Staphylococcus aureus (MRSA, 26%); extended-spectrum β-lactamase–producing Enterobacteriaceae (ESBL, 17%); vancomycin-resistant Enterococcus spp. (VRE, 16%); carbapenem-resistant Enterobacteriaceae (CRE, 1%). MDRO colonization was associated with history of MDRO, care needs, incontinence, and catheters.

Infect Control Hosp Epidemiol 2016;1485–1488


Corresponding author

Address correspondence to James A. McKinnell, MD, Infectious Disease Clinical Outcomes Research Unit (ID-CORE), Division of Infectious Disease, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, 1000 W. Carson Street, Box 466, Torrance, CA 90509 (


Hide All

Authors with equal contribution.



Hide All
1. Antibiotic resistance threats in the United States, 2013. Centers for Disease Control and Prevention website. Published 2013. Accessed August 24, 2016.
2. Overview of nursing facility capacity, financing, and ownership in the United States in 2013. Henry J. Kaiser Family Foundation website. Published 2014. Accessed February 5, 2016.
3. Slayton, RB, Toth, D, Lee, BY, et al. Vital signs: estimated effects of a coordinated approach for action to reduce antibiotic-resistant infections in health care facilities—United States. Morb Mortal Wkly Rep 2015;64:826831.
4. Huang, SS, Septimus, E, Kleinman, K, et al. Targeted versus universal decolonization to prevent ICU infection. New Engl J Med 2013;368:22552265.
5. Bonomo, RA. Multiple antibiotic-resistant bacteria in long-term-care facilities: an emerging problem in the practice of infectious diseases. Clin Infect Dis 2000;31:14141422.
6. Murphy, CR, Quan, V, Kim, D, et al. Nursing home characteristics associated with methicillin-resistant Staphylococcus aureus (MRSA) Burden and Transmission. BMC Infect Dis 2012;12:269.
7. Mitchell, SL, Shaffer, ML, Loeb, MB, et al. Infection management and multidrug-resistant organisms in nursing home residents with advanced dementia. JAMA Intern Med 2014;174:16601667.
8. Shigei, J, Tan, G, Shiao, A, de la Maza, LM, Peterson, EM. Comparison of two commercially available selective media to screen for vancomycin-resistant enterococci. Am J Clin Pathol 2002;117:152155.
9. Smith, PW, Bennett, G, Bradley, S, et al. SHEA/APIC Guideline: infection prevention and control in the long-term care facility. Am J Infect Control 2008;36:504535.
10. Weintrob, AC, Roediger, MP, Barber, M, et al. Natural history of colonization with Gram-negative multidrug-resistant organisms among hospitalized patients. Infect Control Hosp Epidemiol 2010;31:330337.
11. McKinnell, JA, Huang, SS, Eells, SJ, Cui, E, Miller, LG. Quantifying the impact of extranasal testing of body sites for methicillin-resistant Staphylococcus aureus colonization at the time of hospital or intensive care unit admission. Infect Control Hosp Epidemiol 2013;34:161170.


Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed