Skip to main content Accessibility help

Surveillance for Catheter-Associated Bloodstream Infection in Hematology Units: Quantifying the Characteristics of a Practical Case Definition

  • Leon J. Worth (a1) (a2), James Black (a2) (a3), John F. Seymour (a1) (a4), Karin A. Thursky (a1) (a2) and Monica A. Slavin (a1) (a2)...


We evaluated 66 patients in a hematology unit, who used a total of 106 central venous catheters (CVCs), to identify CVC-associated bloodstream infections using standard and modified surveillance case definitions. Compared with the National Nosocomial Infection Surveillance system criteria, a modified case definition used by treating physicians demonstrated 100.0% sensitivity and 94.3% specificity. This case definition provides a practical method for effectively excluding CVC-associated bloodstream infection.


Corresponding author

Department of Infectious Diseases, Peter MacCallum Cancer Centre, St. Andrew's Place, East Melbourne, Victoria, Australia 3002 (


Hide All
1.McKibben, L, Horan, T, Tokars, JI, et al.Guidance on public reporting of healthcare-associated infections: recommendations of the Healthcare Infection Control Practices Advisory Committee. Am J Infect Control 2005;33:217226.
2.Hosoglu, S, Akalin, S, Kidir, V, Suner, A, Kayabas, H, Geyik, MRProspective surveillance study for risk factors of central venous catheter-related bloodstream infections. Am J Infect Control 2004;32:131134.
3.Coyle, VM, McMullan, R, Morris, TC, Rooney, PJ, Hedderwick, S. Catheter-related bloodstream infection in adult haematology patients: catheter removal practice and outcome. J Hosp Infect 2004;57:325331.
4.Worth, LJ, Slavin, MA, Brown, GV, Black, J. Catheter-related bloodstream infections in hematology: time for standardized surveillance? Cancer 2007;109:12151226.
5.Mermel, LA, Farr, BM, Sherertz, RJ, et al.Guidelines for the management of intravascular catheter-related infections. Clin Infect Dis 2001;32:12491272.
6.Horain, TC, Emori, TG. Definitions of key terms used in the NNIS System. Am J Infect Control 1997;25:112116.
7.Lee, TB, Baker, OG, Lee, JT, Scheckler, WE, Steele, L, Laxton, CE. Recommended practices for surveillance. Am J Infect Control 1998;26:277288.
8.German, R, Lee, L, Horan, J, Milstein, R, Pertowski, C, Waller, M. Updated guidelines for evaluating public health surveillance systems. MMWR Morb Mortal Wkly Rep 2001;50(RR13):135.
9.Heipel, D, Ober, JF, Edmond, MB, Bearman, GM. Surgical site infection surveillance for neurosurgical procedures: a comparison of passive surveillance by surgeons to active surveillance by infection control professionals. Am J Infect Control 2007;35:200202.
10.Horan, T, Gaynes, R. Surveillance of Nosocomial Infections. Philadelphia, PA: Lippincott Williams & Wilkins; 2004.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *


Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed