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Surveillance of Hospital-Acquired Central Line–Associated Bloodstream Infections in Pediatric Hematology-Oncology Patients Lessons Learned, Challenges Ahead

  • Aditya H. Gaur (a1), David G. Bundy (a2), Cuilan Gao (a1), Eric J. Werner (a3), Amy L. Billett (a4), Jeff D. Hord (a5), Jane D. Siegel (a6), David Dickens (a7), Cindi Winkle (a6), Marlene R. Miller (a8) and Children's Hospital Association Hematology-Oncology Quality Transformation Collaborative Project...


Across 36 US pediatric oncology centers, 576 central line-associated bloodstream infections (CLABSIs) were reported over a 21-month period. Most infections occurred in those with leukemia and/or profound neutropenia. The contribution of viridans streptococci infections was striking. Study findings depict the contemporary epidemiology of CLABSIs in hospitalized pediatric cancer patients.


Corresponding author

Department of Infectious Diseases, MS 600, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 (


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University of Tennessee at Chattanooga, Tennessee



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