Hostname: page-component-8448b6f56d-qsmjn Total loading time: 0 Render date: 2024-04-20T01:23:18.476Z Has data issue: false hasContentIssue false

Tuberculin Skin Tests Among Medical Students With Prior Bacille-Calmette Guérin Vaccination in a Setting With a High Prevalence of Tuberculosis

Published online by Cambridge University Press:  02 January 2015

Thana Khawcharoenporn
Affiliation:
Division of Infectious Diseases and Infection Control, Faculty of Medicine, Thammasat University Hospital, Pratumthani, Thailand
Anucha Apisarnthanarak*
Affiliation:
Division of Infectious Diseases and Infection Control, Faculty of Medicine, Thammasat University Hospital, Pratumthani, Thailand
Kanokporn Thongphubeth
Affiliation:
Division of Infectious Diseases and Infection Control, Faculty of Medicine, Thammasat University Hospital, Pratumthani, Thailand
Chananart Yuekyen
Affiliation:
Division of Infectious Diseases and Infection Control, Faculty of Medicine, Thammasat University Hospital, Pratumthani, Thailand
Linda M. Mundy
Affiliation:
Saint Louis University School of Public Health, St. Louis, Missouri
*
Division of Infectious Diseases, Faculty of Medicine, Thammasat University Hospital, Pratumthani, Thailand12120 (anapisarn@yahoo.com)

Abstract

Presence of a bacille Calmette-Guérin vaccination scar in medical students was an independent factor associated with initial tuberculin skin test reactions of 10–19 mm (P = .03) and booster effects of 6–9 mm (P = .02). These findings suggest that an initial tuberculin skin test reaction of at least 20 mm or a booster effect of at least 10 mm will reveal tuberculosis among students with prior bacille Calmette-Guérin vaccination.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Franco, C, Zanetta, DM. Assessing occupational exposure as risk for tuberculous infection at a teaching hospital in Sâo Paulo, Brazil. Int J Tuberc Lung Dis 2006;10:384389.Google Scholar
2.Sepulveda, RL, Ferrer, X, Latrach, C, Sorensen, RU. The influence of Calmette-Guérin bacillus immunization on the booster effect of tuberculin testing in healthy young adults. Am Rev Respir Dis 1990;142:2428.Google Scholar
3.Srour-Fihmi, S, Weiler-Ravell, D, Kitzes, R, Chemtob, D. Routine two-step skin testing for tuberculosis in the staff of a geriatric hospital in Israel: booster and conversion rates. J Hosp Infect 2000;46:141146.CrossRefGoogle ScholarPubMed
4.Kassim, S, Zuber, P, Wiktor, SZ, et al.Tuberculin skin testing to assess the occupational risk of Mycobacterium tuberculosis infection among health care workers in Abidjan, Côte d'Ivoire. Int J Tuberc Lung Dis 2000;4:321326.Google Scholar
5.Tan, LH, Kamarulzaman, A, Liam, CK, Lee, TC. Tuberculin skin testing among healthcare workers in the University of Malaya Medical Centre, Kuala Lumpur, Malaysia. Infect Control Hosp Epidemiol 2002;23:584590.Google Scholar
6.García-García, ML, Jiménez-Corona A, , Jiménez-Corona, ME, et al.Factors associated with tuberculin reactivity in two general hospitals in Mexico. Infect Control Hosp Epidemiol 2001;22:8893.Google Scholar
7.Do, AN, Limpakarnjarat, K, Uthaivoravit, W, et al.Increased risk of Mycobacterium tuberculosis infection related to the occupational exposures of health care workers in Chiang Rai, Thailand, Int J Tuberc Lung Dis 1999;3:377381.Google Scholar
8.Keskiner, R, Ergönül, O, Demiroglu, Z, Eren, S, Baykam, N, Dokuzoguz, B. Risk of tuberculous infection among healthcare workers in a tertiary-care hospital in Ankara, Turkey. Infect Control Hosp Epidemiol 2004;25:10671071.Google Scholar
9.Kayanja, HK, Debanne, S, King, C, Whalen, CC. Tuberculosis infection among health care workers in Kampala, Uganda. Int J Tuberc Lung Dis 2005;9:686688.Google Scholar
10.Silva, VM, Cunha, AJ, Kritski, AL. Tuberculin skin test conversion among medical students at a teaching hospital in Rio de Janeiro, Brazil. Infect Control Hosp Epidemiol 2002;23:591594.Google Scholar
11.Pouchot, J, Grasland, A, Collet, C, Coste, J, Esdaile, JM, Vinceneux, P. Reliability of tuberculin skin test measurement. Ann Intern Med 1997;126:210214.Google Scholar
12.Khawcharoenporn, T, Apisarnthanrak, A, Mundy, LM. Assessment of risk for pulmonary tuberculosis after non-reactive tuberculin skin testing among patients with HIV infection in a resource-limited setting. Int J STD AIDS 2008;19:8437.CrossRefGoogle Scholar
13.Riantawan, P, Punnotok, J, Chaisuksuwan, R, Pransujarit, V. Resistance of Mycobacterium tuberculosis to antituberculosis drugs in the Central Region of Thailand, 1996. Int J Tuberc Lung Dis 1998;2:616620.Google ScholarPubMed
14.Yanai, H, Limpakarnjanarat, K, Uthaivoravit, W, Mastro, TD, Mori, T, Tapper, JW. Risk of Mycobacterium tuberculosis infection and disease among health care workers, Chiang Rai, Thailand. Int J Tuberc Lung Dis 2003;7:3645.Google Scholar
15.Padungchan, S, Konjanart, S, Kasiratta, S, Daramas, S, ten Dam, HG. The effectiveness of BCG vaccination of the newborn against childhood tuberculosis in Bangkok. Bull World Health Organ 1986;64:247258.Google Scholar