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Wide Variability in the Use of Antimicrobial Lock Therapy and Prophylaxis among Infectious Diseases Consultants

Published online by Cambridge University Press:  02 January 2015

Philip M. Polgreen ,
Susan E. Beekmann ,
Daniel J. Diekema  and
Robert J. Sherertz
Philip M. Polgreen*
Affiliation:
Division of Infectious Diseases, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa College of Public Health, University of Iowa, Iowa City, Iowa
Susan E. Beekmann
Affiliation:
Division of Infectious Diseases, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa
Daniel J. Diekema
Affiliation:
Division of Infectious Diseases, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa
Robert J. Sherertz
Affiliation:
Wake Forest University School of Medicine, Winston-Salem, North Carolina
*
Division of Infectious Diseases, Department of Internal Medicine, Carver College of Medicine, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, (philip-polgreen@uiowa.edu)
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Abstract

We surveyed infectious diseases physicians to determine their practice patterns with regard to both antimicrobial lock prophylaxis and antimicrobial lock therapy. Antimicrobial lock prophylaxis is relatively uncommon; only 19% of infectious diseases physicians reported using it at least once. Although antimicrobial lock therapy is more commonly used, we found a significant variation in practice patterns.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 31 , Issue 5 , May 2010 , pp. 554 - 557
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2010

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References

1.Mermel, LA, Allon, M, Bouza, E, et al.Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 2009;49(1):1–45.CrossRefGoogle ScholarPubMed
2.Safdar, N, Maki, DG. Use of vancomycin-containing lock or flush solutions for prevention of bloodstream infection associated with central venous access devices: a meta-analysis of prospective, randomized trials. Clin Infect Dis 2006;43(4):474–484.Google Scholar
3.van de Wetering, MD, van Woensel, JB. Prophylactic antibiotics for preventing early central venous catheter gram positive infections in oncology patients. Cochrane Database Syst Rev 2007;(1):CD003295.Google ScholarPubMed
4.Sanders, J, Pithie, A, Ganly, P, et al.A prospective double-blind randomized trial comparing intraluminal ethanol with heparinized saline for the prevention of catheter-associated bloodstream infection in immunosuppressed haematology patients. J Antimicrob Chemother 2008;62(4):809–815.CrossRefGoogle ScholarPubMed
5.Yahav, D, Rozen-Zvi, B, Gafter-Gvili, A, Leibovici, L, Gafter, U, Paul, M. Antimicrobial lock solutions for the prevention of infections associated with intravascular catheters in patients undergoing hemodialysis: systematic review and meta-analysis of randomized, controlled trials. Clin Infect Dis 2008;47(1):83–93.CrossRefGoogle ScholarPubMed
6. Infectious Diseases Society of America Emerging Infections Network's query: antimicrobial lock prophylaxis and treatment of catheter-related bloodstream infections. http://www.int-med.uiowa.edu/research/ein/Antibiotic_lock_survey.pdf. Accessed March 9, 2010.Google Scholar
7.Raad, I, Hanna, H, Jiang, Y, et al.Comparative activities of daptomycin, linezolid, and tigecycline against catheter-related methicillin-resistant Staphylococcus bacteremic isolates embedded in biofilm. Antimicrob Agents Chemother 2007;51(5):1656–1660.CrossRefGoogle ScholarPubMed
8.Fortun, J, Grill, F, Martin-Davila, P, et al.Treatment of long-term intravascular catheter-related bacteraemia with antibiotic-lock therapy. 7 Antimicrob Chemother 2006;58:816–821.CrossRefGoogle ScholarPubMed