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Bupropion in the treatment of depression in Parkinson's disease

  • Maria Załuska (a1) and Agnieszka Dyduch (a2)

A 78-year-old female with a nine-year history of depression was hospitalized due to worsening depression and symptoms associated with Parkinson's disease (PD). Her motor abilities improved on levodopa and the depression improved after a trial of bupropion, following unsuccessful treatment with other antidepressants. We found four reports on successful treatment of depression in PD with bupropion. However, no controlled double-blind studies have been conducted so clinicians should be cautious when administering bupropion in depression in PD.

Corresponding author
Correspondence should be addressed to: Agnieszka Dyduch, Oddział Psychiatrii, Szpital Bielański, Cegłowska 80, 01-809 Warsaw, Poland. Phone: +48 601 178 946; Fax. +48 22 864 47 46. Email:
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International Psychogeriatrics
  • ISSN: 1041-6102
  • EISSN: 1741-203X
  • URL: /core/journals/international-psychogeriatrics
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