Skip to main content

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
Cancel
×
×
Home
  • Home
Article
  • Cited by 5
  • Cited by
    Crossref Citations
    Crossref logo
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.
    Bertrand, Elodie van Duinkerken, Eelco Landeira-Fernandez, J. Dourado, Marcia C. N. Santos, Raquel L. Laks, Jerson and Mograbi, Daniel C. 2017. Behavioral and Psychological Symptoms Impact Clinical Competence in Alzheimer’s Disease. Frontiers in Aging Neuroscience, Vol. 9, Issue. ,
    Au, Bonnie Dale-McGrath, Sydney and Tierney, Mary C. 2017. Sex differences in the prevalence and incidence of mild cognitive impairment: A meta-analysis. Ageing Research Reviews, Vol. 35, Issue. , p. 176.
    Santos, Raquel Luiza Sousa, Maria Fernanda Barroso de Simões Neto, José Pedro Bertrand, Elodie Mograbi, Daniel C. Landeira-Fernandez, Jesus Laks, Jerson and Dourado, Marcia Cristina Nascimento 2017. MacArthur Competence Assessment Tool for Treatment in Alzheimer disease: cross-cultural adaptation. Arquivos de Neuro-Psiquiatria, Vol. 75, Issue. 1, p. 36.
    Chen, Hui-Mei Yeh, Yi-Chun Su, Wei-Lieh Huang, Mei-Feng Chang, Chun-Wei and Chen, Cheng-Sheng 2015. Development and validation of a new performance-based measurement of instrumental activities of daily living in Taiwan. Psychogeriatrics, Vol. 15, Issue. 4, p. 227.
    Sino, Carolien G. M. Sietzema, M. Egberts, T. C. G. and Schuurmans, M. J. 2014. Medication management capacity in relation to cognition and self-management skills in older people on polypharmacy. The journal of nutrition, health & aging, Vol. 18, Issue. 1, p. 44.
    ×
  • Get access
    Add to cart USD35.00
    Check if you have access via personal or institutional login
    Log in Register Recommend to librarian

Capacity to make decisions on medication management in Chinese older persons with mild cognitive impairment and mild Alzheimer's disease

  • Victor Wing-Cheong Lui (a1), Linda Chiu-Wa Lam (a2), Rachel Ching-Man Chau (a2), Ada Wai-Tung Fung (a2), Billy Mou-Lam Wong (a2), Grace Tak-Yu Leung (a1), Kwok-Fai Leung (a3), Helen Fung-Kum Chiu (a2), Jason H. T. Karlawish (a4) and Paul S. Appelbaum (a5)...
Abstract

Background: This study aimed to assess if decisional capacity and the four decision-making abilities related to decisions concerning medication management were impaired among community-dwelling Chinese older persons in Hong Kong with amnestic mild cognitive impairment (MCI) and mild Alzheimer's disease (AD), as compared with cognitively normal older adults.

Methods: Two hundred and ninety-one Chinese community-dwelling older adults were recruited. The four decision-making abilities and decisional capacity were assessed by using the Chinese version of the Assessment of Capacity for Everyday Decision-Making (ACED) and independent clinician ratings based on the definition in the UK Mental Capacity Act 2005, respectively.

Results: Ninety-nine participants (34%) were diagnosed with MCI and ninety-five (33%) with mild AD. Although almost all (96%) of the participants in the MCI group were found to be mentally competent to make decisions on medication management in clinician ratings, their decision-making abilities as measured by the ACED were significantly lower than those of the cognitively normal controls.

Conclusions: Results from this study suggest that abilities related to decisions on medication management are impaired before the clinical diagnosis of dementia is made. Use of specific and structured assessment of the relevant decisional abilities may enhance clinical judgment.

Copyright
COPYRIGHT: © International Psychogeriatric Association 2012
Corresponding author
Correspondence should be addressed to: Dr. Victor Wing-Cheong Lui, Department of Psychiatry, Tai Po Hospital, 9 Chuen On Road, Tai Po, Hong Kong. Phone: +852 26076111; Fax: +852 26623568. Email: victorluiwc@hotmail.com.
References
Hide All
Appelbaum, P. S. (2007). Assessment of patients' competence to consent to treatment. New England Journal of Medicine, 357, 1834–1840.
Appelbaum, P. S. (2010). Consent in impaired populations. Current Neurology and Neuroscience Reports, 10, 367–373.
Chiu, H. F. K. et al. (1998). Prevalence of dementia in Chinese elderly in Hong Kong. Neurology, 50, 1002–1009.
Chiu, H. F. K., Lee, H. C. B., Chung, W. S. and Kwong, P. K. (1994). Reliability and validity of the Cantonese version of the Mini-Mental State Examination: a preliminary study. Hong Kong Journal of Psychiatry, 4 (Suppl. 2), 25–28.
Chu, L. W., Chiu, K. C., Hui, S. L., Yu, G. K., Tsui, W. J. and Lee, P. W. (2000). The reliability and validity of the Alzheimer's Disease Assessment Scale Cognitive Subscale (ADAS-Cog) among the elderly Chinese in Hong Kong. Annual Academy of Medicine Singapore, 29, 474–485.
Department of Constitutional Affairs (2005). The Mental Capacity Act 2005. Available at: http://www.legislation.gov.uk/ukpga/2005/9/contents.
Dunn, L. B., Norwangi, M. A., Palmer, B. W., Jeste, D. V. and Saks, E. R. (2006). Assessing decisional capacity for clinical research or treatment: a review of instruments. American Journal of Psychiatry, 163, 1323–1334.
Folstein, M. F., Folstein, S. E. and McHugh, P. R. (1975). “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189–198.
Gelinas, I., Gauthier, L., McIntyre, M. and Gauthier, S. (1999). Development of a functional measure for persons with Alzheimer's disease: the disability assessment for dementia. American Journal of Occupational Therapy, 53, 471–481.
Grisso, T., Appelbaum, P. S. and Hill-Fotouhi, C. (1997). The MacCAT-T: a clinical tool to assess patients' capacities to make treatment decisions. Psychiatric Services, 48, 1415–1419.
Gurrera, R. J., Moye, J., Karel, M. J., Azar, A. R. and Armesto, J. C. (2006). Cognitive performance predicts treatment decisional abilities in mild to moderate dementia. Neurology, 66, 1367–1372.
Hughes, C. P., Berg, L., Danziger, W. L., Coben, L. A. and Martin, R. L. (1982). A new clinical scale for the staging of dementia. British Journal of Psychiatry, 140, 556–572.
Knapp, M. B. (2010). Legal issues arising in the process of determining decisional capacity in older persons. Care Management Journals, 11, 101–107.
Lai, J. M., Gill, T. M., Cooney, L. M., Bradley, E. H., Hawkins, K. A. and Karlawish, J. H. T. (2008). Everyday decision-making ability in older persons with cognitive impairment. American Journal of Geriatric Psychiatry, 16, 693–696.
Lai, J. M. and Karlawish, J. (2007). Assessing the capacity to make everyday decisions: a guide for clinicians and an agenda for future research. American Journal of Geriatric Psychiatry, 15, 101–111.
Lam, L. C. W. et al. (2008a) Prevalence of very mild and mild dementia in community-dwelling older Chinese people in Hong Kong. International Psychogeriatrics, 20, 135–148.
Lam, L. C. W. et al. (2008b). Use of clinical dementia rating in detecting early cognitive deficits in a community-based sample of Chinese older persons in Hong Kong. Alzheimer Disease and Associated Disorders, 22, 153–157.
Landis, J. R. and Koch, G. G. (1977). The measurement of observer agreement for categorical data. Biometrics, 33, 159–174.
Lui, V. W. C. et al. . (2009) Capacity to make treatment decisions in Chinese older persons with very mild dementia and mild Alzheimer's disease. American Journal of Geriatric Psychiatry, 17, 428–436.
Lui, V. W. C., Lam, L. C. W., Luk, D. N. Y., Chiu, H. F. K. and Appelbaum, P. S. (2010). Neuropsychological performance predicts decision-making abilities in Chinese older persons with mild or very mild dementia. East Asian Archives of Psychiatry, 20, 116–122.
McKhann, G., Drachman, D., Folstein, M., Katzman, R. and Stadlan, E. M. (1984). Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Service Task Force on Alzheimer's disease. Neurology, 34, 939–944.
Mohs, R. C., Rosen, W. G. and Davis, K. L. (1983). The Alzheimer's Disease Assessment Scale: an instrument for assessing treatment efficacy. Psychopharmacology Bulletin, 19, 448–450.
Mok, C. C., Siu, A. M., Chan, W. C., Yeung, K. M., Pan, P. C. and Li, S. W. (2005). Functional disabilities profile of Chinese elderly people with Alzheimer's disease: a validation study on the Chinese version of the disability assessment for dementia. Dementia and Geriatric Cognitive Disorders, 20, 112–119.
Moore, D. J., Moseley, S. and Palmer, B. W. (2008). The clinical usefulness of performance-based assessments of daily functioning for older adults. Geriatrics, 63, 16–20.
Morris, J. C. (1997). Clinical dementia rating: a reliable and valid diagnostic and staging measure for dementia of the Alzheimer type. International Psychogeriatrics, 9 (Suppl. 1), 173–176.
Moye, J., Butz, S. W., Marson, D. C., Wood, E. and Adults Working Group, ABA-APA Capacity Assessment of Older (2007). A conceptual model and assessment template for capacity evaluation in adult guardianship. The Gerontologist, 47, 591–603.
Moye, J. and Naik, A. D. (2011). Preserving rights for individuals facing guardianship. JAMA, 305, 936–937.
Petersen, R. C. et al. (2001). Current concepts in mild cognitive impairment. Archives of Neurology, 58, 1985–1992.
Raad, R., Karlawish, J. and Appelbaum, P. S. (2009). The capacity to vote of persons with serious mental illness. Psychiatric Services, 60, 624–628.
Rosen, W. G., Mohs, R. C. and Davis, K. L. (1984). A new rating scale for Alzheimer's disease. American Journal of Psychiatry, 141, 1356–1364.
Skelton, F., Kunik, M. E., Regev, T. and Naik, A. D. (2010). Determining if an older adult can make and execute decisions to live safely at home: a capacity assessment and intervention model. Archives of Gerontology and Geriatrics, 50, 300–305.
Yu, F. O. T., Lui, V. W. C., Lam, L. C. W., Chiu, H. F. K., Karlawish, J. H. T. and Appelbaum, P. S. (2009) Assessment of capacity to make financial decision in Chinese psychogeriatric Patients: a pilot study. Hong Kong Journal of Psychiatry, 19, 82–86.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

International Psychogeriatrics
  • ISSN: 1041-6102
  • EISSN: 1741-203X
  • URL: /core/journals/international-psychogeriatrics
Please enter your name
Please enter a valid email address
Who would you like to send this to? *

CAPTCHA *

Skip to the audio challenge
×

Keywords:

Metrics

Full text views

Total number of HTML views: 6
Total number of PDF views: 52 *
Loading metrics...

Abstract views

Total abstract views: 330 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 12th June 2018. This data will be updated every 24 hours.

Cancel
Confirm
×