Hostname: page-component-8448b6f56d-tj2md Total loading time: 0 Render date: 2024-04-18T09:48:29.068Z Has data issue: false hasContentIssue false
  • English
  • Français

Comparison of QOL between patients with different degenerative dementias, focusing especially on positive and negative affect

Published online by Cambridge University Press:  29 March 2016

Kairi Kurisu ,
Seishi Terada ,
Etsuko Oshima ,
Makiko Horiuchi ,
Nao Imai ,
Mayumi Yabe ,
Osamu Yokota ,
Takeshi Ishihara  and
Norihito Yamada
Kairi Kurisu
Affiliation:
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Seishi Terada*
Affiliation:
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Etsuko Oshima
Affiliation:
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Makiko Horiuchi
Affiliation:
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Nao Imai
Affiliation:
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Mayumi Yabe
Affiliation:
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Osamu Yokota
Affiliation:
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Takeshi Ishihara
Affiliation:
Department of Psychiatry, Kawasaki Medical School, Okayama, Japan
Norihito Yamada
Affiliation:
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
*
Correspondence should be addressed to: Dr. Seishi Terada at Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700–8558, Japan. Phone: +81-86-235-7242; Fax: +81-86-235-7246. Email: terada@cc.okayama-u.ac.jp.
Get access Rights & Permissions [Opens in a new window]

Abstract

Background:

Quality of life (QOL) has become an important outcome measure in the care of dementia patients. However, there have been few studies focusing on the difference in QOL between different dementias.

Methods:

Two-hundred seventy-nine consecutive outpatients with Alzheimer's disease (AD), dementia with Lewy bodies (DLB) or frontotemporal dementia (FTD) were recruited. The QOL was evaluated objectively using the QOL Questionnaire for Dementia (QOL-D).The QOL-D comprises six domains: positive affect, negative affect and actions, communication, restlessness, attachment to others, and spontaneity. General cognition, daily activities, and behavioral and psychological symptoms of dementia were also evaluated.

Results:

The scores of positive affect of QOL-D of AD patients were significantly higher than those of patients with DLB or FTD (AD 3.1 ± 0.8, DLB 2.6 ± 0.9, FTD 2.6 ± 0.7). The scores of negative affect and action of QOL-D of FTD patients were significantly higher than those of patients with AD or DLB (FTD 2.0 ± 0.8, AD 1.4 ± 0.5, DLB 1.5 ± 0.6). The apathy scores of FTD and DLB patients were significantly higher than those of patients with AD. The disinhibition scores of FTD patients were significantly higher than those of patients with AD or DLB.

Conclusions:

The apathy of FTD and DLB patients and depression of DLB patients might affect the lower positive affect of FTD and DLB patients compared to AD patients. The disinhibition of FTD patients might affect the abundance of negative affect & actions in FTD patients compared to AD and DLB patients.

Keywords

Alzheimer's diseasedementiadementia with Lewy bodiesfrontotemporal dementianegative affectpositive affectquality of life (QOL)
Type
Research Article
Information
International Psychogeriatrics , Volume 28 , Issue 8 , August 2016 , pp. 1355 - 1361
Copyright
Copyright © International Psychogeriatric Association 2016 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Banerjee, S. et al. (2009). What do we know about quality of life in dementia? A review of the emerging evidence on the predictive and explanatory value of disease specific measures of health related quality of life in people with dementia. International Journal of Geriatric Psychiatry, 24, 15–24. doi:10.1002/gps.2090.CrossRefGoogle ScholarPubMed
Beerens, H. C., Zwakhalen, S. M., Verbeek, H., Ruwaard, D. and Hamers, J. P. (2013). Factors associated with quality of life of people with dementia in long-term care facilities: a systematic review. International Journal of Nursing Studies, 50, 1259–1270. doi:10.1016/j.ijnurstu.2013.02.005.CrossRefGoogle ScholarPubMed
Boström, F., Jönsson, L., Minthon, L. and Londos, E. (2007). Patients with dementia with Lewy bodies have more impaired quality of life than patients with Alzheimer disease. Alzheimer Disease and Associated Disorders, 21, 150–154. doi:10.1097/WAD.0b013e318065c4a9.CrossRefGoogle ScholarPubMed
Brod, M., Stewart, A. L., Sands, L. and Walton, P. (1999). Conceptualization and measurement of quality of life in dementia: the dementia quality of life instrument (DQoL). Gerontologist, 39, 25–35.CrossRefGoogle ScholarPubMed
Casey, A. N., Low, L. F., Goodenough, B., Fletcher, J. and Brodaty, H. (2014). Computer-assisted direct observation of behavioral agitation, engagement, and affect in long-term care residents. Journal of the American Medical Directors Association, 15, 514–520. doi:10.1016/j.jamda.2014.03.006.CrossRefGoogle ScholarPubMed
Ettema, T. P., Dröes, R. M., de Lange, J., Mellenbergh, G. J. and Ribbe, M. W. (2005). A review of quality of life instruments used in dementia. Quality of Life Research, 14, 675–686.CrossRefGoogle ScholarPubMed
Figari-Jordan, R. et al. (2012). Comparison of quality of life and disability in three different dementias. Neurology, 78 (Suppl. 1), P07.180. doi:10.1212/WNL.78.1_MeetingAbstracts.P07.180.CrossRefGoogle Scholar
Folstein, M. F., Folstein, S. E. and McHugh, P. R. (1975). Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189–198.Google Scholar
Hirono, N. et al. (1997). Japanese version of the Neuropsychiatric Inventory: a scoring system for neuropsychiatric disturbance in dementia patients. Brain and Nerve, 49, 266–271(in Japanese with English abstract).Google ScholarPubMed
Hokoishi, K. et al. (2001). Interrater reliability of the physical self-maintenance scale and the instrumental activities of daily living scale in a variety of health professional representatives. Aging and Mental Health, 5, 38–40.CrossRefGoogle Scholar
Hughes, C. P., Berg, L., Danziger, W. L., Coben, L. A. and Martin, R. L. (1982). A new clinical scale for the staging of dementia. British Journal of Psychiatry, 140, 566–572.Google Scholar
Jonker, C., Gerritsen, D. L., Bosboom, P. R. and Van Der Steen, J. T. (2004). A model for quality of life measures in patients with dementia: Lawton's next step. Dementia and Geriatric Cognitive Disorders, 18, 159–164. doi:10.1159/000079196.CrossRefGoogle Scholar
Kashiwagi, M., Tamiya, N., Sato, M. and Yano, E. (2013). Factors associated with the use of home-visit nursing services covered by the long term care insurance in rural Japan: a cross-sectional study. BMC Geriatrics, 13, 1. doi:10.1186/1471-2318-13-1.Google Scholar
Klatka, L. A., Louis, E. D. and Schiffer, R. B. (1996). Psychiatric features in diffuse Lewy body disease: a clinicopathologic study using Alzheimer's disease and Parkinson's disease comparison groups. Neurology, 47, 1148–1152.CrossRefGoogle ScholarPubMed
Kolanowski, A. M., Van Haitsma, K., Meeks, S. and Litaker, M. (2014). Affect balance and relationship with well-being in nursing home residents with dementia. American Journal of Alzheimer's Disease and Other Dementias, 29, 457–462. doi:10.1177/1533317513518657.CrossRefGoogle ScholarPubMed
Lawton, M. P. and Brody, E. M. (1969). Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist, 9, 179–186.CrossRefGoogle ScholarPubMed
McKeith, I. G. et al. (2005). Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology, 65, 1863–1872.CrossRefGoogle ScholarPubMed
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D. and Stadlan, E. M. (1984). Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's Disease. Neurology, 34, 939–944.CrossRefGoogle ScholarPubMed
Neary, D. et al. (1998). Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology, 51, 1546–1554.CrossRefGoogle ScholarPubMed
Nierenberg, A. A., Bentley, K. H., Farabaugh, A. H., Fava, M. and Deckersbach, T. (2012). The absence of depressive symptoms is not the presence of wellness: validation of the clinical positive affect scale. Australian & New Zealand Journal of Psychiatry, 46, 1165–1172. doi:10.1177/0004867412459810.CrossRefGoogle Scholar
Politis, A. M., Vozzella, S., Mayer, L. S., Onyike, C. U., Baker, A. S. and Lyketsos, C. G. (2004). A randomized, controlled, clinical trial of activity therapy for apathy in patients with dementia residing in long-term care. International Journal of Geriatric Psychiatry, 19, 1087–1094. doi:10.1002/gps.1215.CrossRefGoogle ScholarPubMed
Rankin, K. P., Baldwin, E., Pace-Savitsky, C., Kramer, J. H. and Miller, B. L. (2005). Self awareness and personality change in dementia. Journal of Neurology, Neurosurgery & Psychiatry, 76, 632–639. doi:10.1136/jnnp.2004.042879.CrossRefGoogle ScholarPubMed
Riazi, A., Bradley, C., Barendse, S. and Ishii, H. (2006). Development of the Well-being Questionnaire short-form in Japanese: the W-BQ12. Health and Quality of Life Outcomes, 4, 40. doi:10.1186/1477-7525-4-40.CrossRefGoogle ScholarPubMed
Schreiner, A. S.,Yamamoto, E. and Shiotani, H. (2005). Positive affect among nursing home residents with Alzheimer's dementia: the effect of recreational activity. Aging & Mental Health, 9, 129–134. doi:10.1080/13607860412331336841.CrossRefGoogle ScholarPubMed
Terada, S. et al. (2002). Development and evaluation of a health-related quality of life questionnaire for the elderly with dementia in Japan. International Journal of Geriatric Psychiatry, 27, 851–858. doi:10.1002/gps.711.CrossRefGoogle Scholar
Yamane, Y., Sakai, K. and Maeda, K. (2011). Dementia with Lewy bodies is associated with higher scores on the geriatric depression scale than is Alzheimer's disease. Psychogeriatrics, 11, 157–165. doi:10.1111/j.1479-8301.2011.00368.x.CrossRefGoogle ScholarPubMed