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A case in which mirtazapine reduced auditory hallucinations in a patient with Parkinson disease

  • Tomoyuki Nagata (a1), Shunichiro Shinagawa (a1), Kenji Tagai (a1) and Kazuhiko Nakayama (a1)
Abstract
ABSTRACT

A 48-year-old woman with Parkinson disease (PD) suffered from auditory hallucinations (AH). We had treated her with a reduction in antiparkinsonian agents and the use of atypical antipsychotic agents. However, her symptoms did not improve, and her extrapyramidal symptoms (EPS) worsened. To lessen her depressive symptoms, treatment with a new-generation antidepressant, mirtazapine (MRZ), was commenced. The patient's AH gradually decreased with no worsening of EPS, and the AH disappeared 4 weeks after the commencement of treatment with MRZ. The present case suggests the effectiveness of MRZ for the treatment of refractory AHs in patients with PD.

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Corresponding author
Correspondence should be addressed to: Tomoyuki Nagata, Department of Psychiatry, Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo 105-8461, Japan. Phone: +81 334 331 111; Fax: +81 334 370 228. Email: t.nagata@jikei.ac.jp.
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

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International Psychogeriatrics
  • ISSN: 1041-6102
  • EISSN: 1741-203X
  • URL: /core/journals/international-psychogeriatrics
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