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Compared with the rather uniform cognitive syndrome in Alzheimer's disease (AD), behavioral and psychological symptoms of dementia (BPSD) are considerably more heterogeneous in terms of incidence, prevalence, and association with disease duration and severity of dementia (Hope et al., 1999). The neurobiologic basis of AD is obviously less of a determinant of noncognitive symptoms than of cognitive symptoms. Therefore, the possible psychological and social causes of BPSD, such as premorbid personality, should be considered. Underlying personality traits not only shape a person's response to normal aging, but also set the stage for a range of responses to age-related stress and brain disease (Agronin, 1998).
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