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Raising the bar: a comparative analysis of patients with Early Onset Alzheimer's disease

  • Tor Atle Rosness (a1), Knut Engedal (a2) and Zeina Chemali (a3)
Extract

Early onset Alzheimer's disease (EOAD) poses considerable challenges to physicians both in diagnostics and treatment, to patients and caregivers trying to cope with a debilitating illness at a young age and a healthcare system that is not geared to cater to degenerating illnesses striking young persons (Van Vliet et al., 2012). Routine procedures and screening measures for elderly people possibly stricken by dementia do not assess younger dementia patients in a favourable fashion. Physicians at an outpatient clinic diagnosing elderly patients, with well established standardized cognitive batteries for an older age norm, i.e. above 65 years may have unadjusted assumptions to account for in younger patients with symptoms of EOAD (Smits et al., 2012). Although a common battery of tests is internationally widely applied in the evaluation of cognitive impairment, these tests have not been validated extensively in a sample population of AD under the age of 65.

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References
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Chemali, Z., Schamber, S., Tarbi, E., Acar, D. and Avila-Urizar, M. (2012). Diagnosing early onset dementia and then what? A frustrating system of aftercare resources. Internal Journal of General Medicine, 5, 8186.
Fairjones, S. E., Vuletich, E. J., Pestell, C. and Panegyres, P. K. (2011). Exploring the role of cognitive reserve in early-onset dementia. American Journal of Alzheimers Disease and Other Dementias, 26, 139144.
Rosness, T. A., Barca, M. L. and Engedal, K. (2010). Occurrence of depression and its correlates in early onset dementia patients. International Journal of Geriatric Psychiatry, 25, 704711.
Smits, L. et al. (2012). Early onset Alzheimer's disease is associated with a distinct neuropsychological profile. Journal of Alzheimers Disease, 30, 101108.
Van Vliet, D. et al. (2012). Time to diagnosis in young-onset dementia as compared with late-onset dementia. Psychological Medicine, 43, 423432.
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International Psychogeriatrics
  • ISSN: 1041-6102
  • EISSN: 1741-203X
  • URL: /core/journals/international-psychogeriatrics
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