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Cannabis and hyperemesis

Published online by Cambridge University Press:  13 June 2014

Ella Harris ,
Michael McDonagh  and
Noel Kennedy
Ella Harris*
Affiliation:
4th year GP registrar on the TCD/HSE Specialist Training Programme in General Practice, Dublin, Ireland
Michael McDonagh
Affiliation:
St Patrick's University Hospital, Dublin, Ireland
Noel Kennedy
Affiliation:
St Edmundsbury Hospital, Lucan, Co Dublin, Ireland
*
*Correspondence E-mail: ellyharris@gmail.com
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Abstract

The adverse effects of marijuana are well documented, as well as its positive therapeutic uses. Cannabis has traditionally been associated with an antiemetic action following acute ingestion and synthetic cannabinoids have an established use as antiemetics for chemotherapy induced nausea. However, there has been limited recognition of chronic cannabis use as a cause of cyclic vomiting syndrome. Cannabinoid hyperemesis was first identified by Allen er al in 2004. Compulsive bathing was also described as part of the clinical picture. This same syndrome has been confirmed a number of times in the medical literature in the interim. The condition has, to our knowledge, never been reported, in a psychiatric patient.

Type
Case Reports
Information
Irish Journal of Psychological Medicine , Volume 27 , Issue 1 , March 2010 , pp. 47 - 48
Copyright
Copyright © Cambridge University Press 2010

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References

1.Kumar, RN, Chambers, WA, Pertwee, RG. Pharmacological actions and therapeutic uses of cannabis and cannabinoids. Anaesthesia 2001; 56(11): 1059–68.CrossRefGoogle ScholarPubMed
2.Tramer, MR, Carroll, D, Campbell, FA, Reynolds, DJ, Moore, RA, McQuay, HJ. Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review. BMJ 2001;323(7303): 16–21.CrossRefGoogle ScholarPubMed
3.Allen, JH, de Moore, GM, Heddle, R, Twartz, JC. Cannabinoid hyperemesis: cyclical hyperemesis in association with chronic cannabis abuse. Gut 2004; 53(11): 1566–70.CrossRefGoogle ScholarPubMed
4.Boeckxstaens, GE. [Cannabinoid hyperemesis with the unusual symptom of compulsive bathing]. Ned Tijdschr Geneeskd 2005; 149(26): 1468–71.Google ScholarPubMed
5.Wallace, D, Martin, AL, Park, B. Cannabinoid hyperemesis: marijuana puts patients in hot water. Australas Psychiatry 2007; 15(2): 156–8.CrossRefGoogle ScholarPubMed
6.Chepyala, P, Olden, KW. Cyclic Vomiting and Compulsive Bathing With Chronic Cannabis Abuse. Clin Gastroenterol Hepatol 2008; May 2.CrossRefGoogle ScholarPubMed
7.Pareek, N, Fleisher, DR, Abell, T. Cyclic vomiting syndrome: what a gastroenterologyist needs to know. Am J Gastroenterol 2007; 102(12): 2832–40.CrossRefGoogle ScholarPubMed
8.Fleisher, DR, Gornowicz, B, Adams, K, Burch, R, Feldman, EJ. Cyclic Vomiting Syndrome in 41 adults: the illness, the patients, and problems of management. BMC Med 2005; 3:20.CrossRefGoogle Scholar
9.Pertwee, RG. Cannabinoids and the gastrointestinal tract. Gut 2001; 48(6): 859–67.CrossRefGoogle ScholarPubMed
10.Parker, LA, Kwiatkowska, M, Burton, P, Mechoulam, R. Effect of cannabinoids on lithiuminduced vomiting in the Suncus murinus (house musk shrew). Psychopharmacology (Berl) 2004; 171(2): 156–61.CrossRefGoogle ScholarPubMed
11.McCallum, RW, Soykan, I, Sridhar, KR, Ricci, DA, Lange, RC, Plankey, MW. Delta-9-tetrahydrocannabinol delays the gastric emptying of solid food in humans: a double-blind, randomized study. Aliment Pharmacol Ther 1999; 13(1): 77–80.CrossRefGoogle ScholarPubMed
12.Pagotto, U, Marsicano, G, Cota, D, Lutz, B, Pasquali, R. The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev 2006; 27(1): 73–100.CrossRefGoogle ScholarPubMed
13.Hayakawa, K, Mishima, K, Abe, Ket al.Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism. Neuroreport 2004; 15(15): 2381–5.CrossRefGoogle ScholarPubMed