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Roberts, Kinley A.
O’Rourke, Killian E. T.
and
Ross, Owen A.
2013.
Stroke Genetics.
p.
81.
Published online by Cambridge University Press: 13 June 2014
A 31 year-old man with a history of a depressive episode presented with acute severe ‘thunderclap’ headache. Magnetic resonance imaging (MRI) revealed abnormalities typical of cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL), which was subsequently confirmed by genetic analysis. The psychiatric features of this genetic cause of depression and headache are discussed.