Methadone and its effect on QTc prolongation

Deirdre Hussey; Catherine McCarthy; Eamon Keenan

doi:10.1017/S0790966700017961

Published online by Cambridge University Press: 13 June 2014

Deirdre Hussey ,

Catherine McCarthy and

Eamon Keenan

Show author details

Deirdre Hussey: Affiliation:
National Drug Treatment Centre, Pearse Street, Dublin, Ireland
Catherine McCarthy: Affiliation:
National Drug Treatment Centre, Pearse Street, Dublin, Ireland
Eamon Keenan: Affiliation:
National Drug Treatment Centre, Pearse Street, Dublin, Ireland

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'

References

1.Wesohules, DJ, McMath, JA, Gallagher, Ret al.Methadone and the hospice patient: prescribing trends in the home-care setting. Pain Med 2003; 4: 269–76.CrossRef Google Scholar

2.Niveau, G, Rougemont, AL, La Harpe, R. Methadone Maintenance treatment, criminality and overdose – related deaths. An ecological study, 1983 – 1999. Eur J Public Health 2002; 12: 224–7.CrossRef Google Scholar PubMed

3.McCaffrey, BR. Methadone treatment: our vision for the future. J Addict Dis. 2001; 20:93–101Google Scholar

4.Stitcherling, C, Schaer, B, Ammann, Pet al, Methadone-induced Torsades de Pointes tachycardias. Swiss Med Weekly 2005 135: 282–285.Google Scholar

5.European Agency for the evaluation of Medicinal Products, EMEA public statement to suspend the marketing authorization for Orlaam (levacetylmethadol) in the European Union. 04 19 2001.Google Scholar

6.Deamer, RL, Nllson, DR, Clark, DSet al.Torsades de Pointes associated with high dose levomethadyl acetate (ORLAAM) J Addict Dos 2001; 20: 7–14CrossRef Google Scholar

Stitcherling, C, Schaer, B, Ammann, Pet al, Methadone -induced Torsades de Pointes tachycardias. Swiss Med Weekly 2005 135: 282–285.Google Scholar

7.Gupta, A, Lawrence, A, Krishnan, Ket al, Current Concepts in the mechanism and management of drug-induced QT prolongation and Torsades de Pointes. American Heart Journal, 06 2007 153(6): 891–899.CrossRef Google Scholar

8.Martell, BAet al, Impact of methadone treatment on cardiac repolarisation and conduction in opioid users. Am J cardiol 2005; 95: 915–918CrossRef Google Scholar

9.Krantz, MJ, Lewkowiez, L, Hays, Het al.Torsades depointes associated with very high dose methadone. Ann Intern Med 2002; 137: 501–4CrossRef Google Scholar

10.Whret, G, Voide, C, Gex-Fabry, Met al.Drug Induced Long QT Syndrome in Injection drug users receiving Methadone. Arch Intern Med 2006:166: 1280–1287Google Scholar

11.Fanoe, S, Huidt, C, Ege, Pet al, Syncope and QT prolongation among patients treated with methadone for heroin dependence in the City of Copenhagen. Heart 2007 09; 93(9) 1051–5CrossRef Google Scholar PubMed

12.Lamont, P, Hunt, S, A twist on Torsade: A Prolonged QT interval on Methadone. J Gen Intern Med 206, 11 21 (11), C9–C12CrossRef Google Scholar

Please list any fees and grants from, employment by, consultancy for, shared ownership in or any close relationship with, at any time over the preceding 36 months, any organisation whose interests may be affected by the publication of the response. Please also list any non-financial associations or interests (personal, professional, political, institutional, religious or other) that a reasonable reader would want to know about in relation to the submitted work. This pertains to all the authors of the piece, their spouses or partners.

Article contents

Methadone and its effect on QTc prolongation

Abstract

References

This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

Article contents

Methadone and its effect on QTc prolongation

Abstract

References

Send article to Kindle

Send article to Dropbox

Send article to Google Drive

Reply to: Submit a response

Your details

Conflicting interests