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Family study in sickle Cell disease in Nigeria

  • F. E. A. Lesi (a1) and Ekpo E. E. Bassey (a1)
Extract

A pilot survey has been made of Nigerian families at risk of producing SS haemoglobin homozygotes. Genotypes of parents and off-spring were investigated in twenty-five families. There is a suggestion that more SS children are produced where the first born suffers from haemoglobin SS disease. Mortality among offspring was higher in the study population than in the general population.

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References
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Konotey-Ahulu, F.D.I. (1970) Maintenance of high sickling rate in Africa—role of polygamy. J. trop. Med. Hyg. 73, 19.
Lehman, H. (1968) Haemoglobinopathies. In: Health Problems in Developing States. Proc. 4th Rehovoth Conference Israel, 1967. Edited by Moshe, Prywes & Michael, Davies. Grune & Stratton, New York.
Roberts, D. F. & Boyo, A. E. (1960) On the stability of haemoglobin gene frequencies in West Africa. Ann. hum. Genet. 24, 375.
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Journal of Biosocial Science
  • ISSN: 0021-9320
  • EISSN: 1469-7599
  • URL: /core/journals/journal-of-biosocial-science
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