Skip to main content
    • Aa
    • Aa

Oxidative stress indicators and metabolic adaptations in response to the omission of the dry period in dairy cows

  • Roberto Mantovani (a1), Sandy Sgorlon (a2), Lieta Marinelli (a3), Lucia Bailoni (a1), Giovanni Bittante (a1) and Gianfranco Gabai (a3)...

The effects of dry period omission on oxidative stress and metabolic indicators around calving were studied. Seventeen Italian Friesian cows were randomly assigned to two groups, homogeneous for milk yield and parity, and managed either with a traditional 55-d dry off period (n=8) or continuously milked till parturition (n=9). Between 60 d before expected calving and 90 d after calving, body condition (BCS) was recorded and blood samples were collected to measure cortisol, urea, cholesterol, glucose, NEFA, triglycerides, insulin, malondialdehyde (MDA), total glutathione (GSH) and glutathione peroxidase (GPx) activity. BCS changes after calving were not different between the two groups. The normally dried group showed lower (P<0·05) glucose concentrations on day 7 before calving, greater (P<0·01) non-esterified fatty acid concentrations at 7 d and 15 d after calving, and greater (P<0·01) triglyceride concentrations for all the period before calving. On the other hand, plasma MDA was not different between groups. On average, plasma GSH concentrations were greater in continuously milked cows after calving (P<0·05), while plasma GPx was greater with continuous milking up to parturition (P<0·01). The results confirmed that omitting the dry period leads to an improved energy balance. The degree of oxidative stress was not detrimental for animal health, and the slight modifications of GPx observed prepartum were possibly related to continuous milk secretion. The differences in plasma GSH observed after calving may depend upon sulphur amino acid sparing in continuously milked cows.

Corresponding author
*For correspondence; e-mail:
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

JB Andersen , TG Madsen , T Larsen , KL Ingvartsen & MO Nielsen 2005 The effects of dry periods versus continuous lactation on metabolic status and performance in periparturient cows. Journal of Dairy Science 88 35303541

EL Annen , RJ Collier , MA McGuire , JL Vicini , JM Ballam & MJ Mormore 2004b Effect of modified dry period lengths and somatotropin protocols on milk yield and composition of primiparous and multiparous cows. Journal of Dairy Science 87 37463761

CR Baumrucker , PA Pocius & TL Riss 1981 Glutathione utilization by lactating bovine mammary secretory tissue in vitro. Biochemical Journal 198 243246

U Bernabucci , B Ronchi , N Lacetera & A Nardone 2002 Markers of oxidative status in plasma and erythrocytes of transition dairy cows during hot season. Journal of Dairy Science 85 21732179

AV Capuco & RM Akers 1999 Mammary involution in dairy animals. Journal of Mammary Gland Biology and Neoplasia 4 137144

AJ Edmonson , IJ Lean , LD Farver , T Farver & G Webster 1989 A body condition scoring chart for Holstein dairy cows. Journal of Dairy Science 72 6878

RR Grummer & RR Rastani 2004 Why re-evaluate dry period length? Journal of Dairy Science 87(E. Suppl.) E77E85

SL Johnston , KE Kitson , JW Tweedle , SR Davis & J Lee 2004 γ-Glutamyl transpeptidase inhibition suppresses milk protein synthesis in isolated ovine mammary cells. Journal of Dairy Science 87 321329

JK Miller , E Brzezinska-Slebodzinska & FC Madsen 1993 Oxidative stress, antioxidants, and animal function. Journal of Dairy Science 76 28122823

CA Rotz , DL Zartman & KL Crandal 2005 Economic and environmental feasibility of a perennial cow dairy farm. Journal of Dairy Science 88 30093019

M Tanaka , Y Kamiya , M Kamiya , S Shioya & Y Nakai 2007 Antiradical function of sulfhydryl residues and oxidative stress markers in dairy cattle plasma. Animal Science Journal 78 6165

MS Weber , S Purup , M Vestergaard , RM Akers & K Sejrsen 2000 Regulation of local synthesis of insulin-like growth factor-I and binding proteins in mammary tissue. Journal of Dairy Science 83 3037

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Journal of Dairy Research
  • ISSN: 0022-0299
  • EISSN: 1469-7629
  • URL: /core/journals/journal-of-dairy-research
Please enter your name
Please enter a valid email address
Who would you like to send this to? *



Full text views

Total number of HTML views: 2
Total number of PDF views: 14 *
Loading metrics...

Abstract views

Total abstract views: 75 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 24th June 2017. This data will be updated every 24 hours.