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Birth size is not associated with depressive symptoms from adolescence to middle-age: results from the Northern Swedish Cohort study

  • K. Rajaleid (a1) (a2), U. Janlert (a3), A. Hjern (a2) (a4), H. Westerlund (a1) and A. Hammarström (a1) (a5)...
Abstract

Low birth weight has been shown to be related to increased risk of depression later in life – but the evidence is not conclusive. We examined the association of size at birth with repeatedly measured depressive symptoms in 947 individuals from the Northern Swedish Cohort, a community-based age-homogeneous cohort born in 1965, and followed with questionnaires between ages 16 and 43 (participation rate above 90% in all the surveys). Information on birth size was retrieved from archived birth records. Length of gestation was known for a subsample of 512 individuals (54%). We studied the association of birth weight and ponderal index with self-reported depressive symptoms at ages 16, 21, 30 and 43; with the life-course average of depressive symptoms score and with longitudinal trajectories of depressive symptoms retrieved by latent class growth analysis. Socioeconomic background, mental illness or alcohol problems of a parent, exposure to social adversities in adolescence and prematurity were accounted for in the analyses. We did not find any relationship between weight or ponderal index at birth and our measure of depressive symptoms between ages 16 and 43 in a series of different analyses. Adjustment for length of gestation did not alter the results. We conclude that size at birth is not associated with later-life depressive symptoms score in this cohort born in the mid-1960s in Sweden. The time and context need to be taken into consideration in future studies.

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Corresponding author
Address for correspondence: Kristiina Rajaleid, Stress Research Institute, Stockholm University SE-106 91 Stockholm, Sweden. E-mail: Kristiina.Rajaleid@su.se
References
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1. Papachristou, E, Frangou, S, Reichenberg, A. Expanding conceptual frameworks: life course risk modelling for mental disorders. Psychiatry Res. 2013; 206, 140145.
2. Colman, I, Ataullahjan, A. Life course perspectives on the epidemiology of depression. Can J Psychiatry. 2010; 55, 622632.
3. Wojcik, W, Lee, W, Colman, I, Hardy, R, Hotopf, M. Foetal origins of depression? A systematic review and meta-analysis of low birth weight and later depression. Psychol Med. 2013; 43, 112.
4. Loret de Mola, C, de França, GV, Quevedo Lde, A, Horta, BL. Low birth weight, preterm birth and small for gestational age association with adult depression: systematic review and meta-analysis. Br J Psychiatry. 2014; 205, 340347.
5. Pariante, CM, Lightman, SL. The HPA axis in major depression: classical theories and new developments. Trends Neurosci. 2008; 31, 464468.
6. Miller, GE, Chen, E, Zhou, ES. If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans. Psychol Bull. 2007; 133, 2545.
7. Colman, I, Ploubidis, GB, Wadsworth, ME, Jones, PB, Croudace, TJ. A longitudinal typology of symptoms of depression and anxiety over the life course. Biol Psychiatry. 2007; 62, 12651271.
8. Alati, R, Lawlor, DA, Mamun, AA, et al. Is there a fetal origin of depression? Evidence from the Mater University Study of Pregnancy and its outcomes. Am J Epidemiol. 2007; 165, 575582.
9. Herva, A, Pouta, A, Hakko, H, et al. Birth measures and depression at age 31 years: the Northern Finland 1966 birth cohort study. Psychiatry Res. 2008; 160, 263270.
10. Dahly, DL, Adair, LS, Bollen, KA. A structural equation model of the developmental origins of blood pressure. Int J Epidemiol. 2009; 38, 538548.
11. Wiles, NJ, Peters, TJ, Leon, DA, Lewis, G. Birth weight and psychological distress at age 45-51 years: results from the Aberdeen children of the 1950s cohort study. Br J Psychiatry. 2005; 187, 2128.
12. Gale, CR, Martyn, CN. Birth weight and later risk of depression in a national birth cohort. Br J Psychiatry. 2004; 184, 2833.
13. Jung, T, Wickrama, KAS. An introduction to latent class growth analysis and growth mixture modeling. Soc Personal Psychol Compass. 2008; 2, 302317.
14. Hammarström, A, Janlert, U. Cohort profile: the northern Swedish cohort. Int J Epidemiol. 2012; 41, 15451552.
15. Hammarström, A, Westerlund, H, Kirves, K, et al. Addressing challenges of validity and internal consistency of mental health measures in a 27-year longitudinal cohort study—the Northern Swedish Cohort study. BMC Med Res Methodol. 2016; 16, 4.
16. Nagin, DS. Group-based modeling of development. 2005. Harvard University Press: Cambridge, MA.
17. Muthen, LK, Muthen, BO. Mplus user’s guide. 2007. Muthen & Muthen: Los Angeles, CA.
18. Wickrama, KA, Conger, RD, Abraham, WT. Early family adversity, youth depressive symptom trajectories, and young adult socioeconomic attainment: a latent trajectory class analysis. Adv Life Course Res. 2008; 13, 161192.
19. Nylund, KL, Asparouhov, T, Muthen, BO. Deciding on the number of classes in latent class analysis and growth mixture modeling: a Monte Carlo simulation study. Struct Equ Model. 2007; 14, 535569.
20. Thompson, C, Syddall, H, Rodin, I, Osmond, C, Barker, DJ. Birth weight and the risk of depressive disorder in late life. Br J Psychiatry. 2001; 179, 450455.
21. Gustafsson, PE, Janlert, U, Theorell, T, Hammarström, A. Is body size at birth related to circadian salivary cortisol levels in adulthood? Results from a longitudinal cohort study. BMC Public Health. 2010; 10, 346.
22. Gustafsson, PE, Janlert, U, Theorell, T, Westerlund, H, Hammarström, A. Fetal and life course origins of serum lipids in mid-adulthood: results from a prospective cohort study. BMC Public Health. 2010; 10, 484.
23. Leino-Arjas, P, Rajaleid, K, Mekuria, G, et al. Trajectories of musculoskeletal pain from adolescence to middle age: the role of early depressive symptoms, a 27-year follow-up of the Northern Swedish Cohort. Pain. 2017 [Epub ahead of print].
24. Almquist, YB, Landstedt, E, Hammarström, A. Associations between social support and depressive symptoms: social causation or social selection-or both? Eur J Public Health. 2017; 27, 8489.
25. Landstedt, E, Almquist, YB, Eriksson, M, Hammarström, A. Disentangling the directions of associations between structural social capital and mental health: longitudinal analyses of gender, civic engagement and depressive symptoms. Soc Sci Med. 2016; 163, 135143.
26. Mehio-Sibai, A, Feinleib, M, Sibai, TA, Armenian, HK. A positive or a negative confounding variable? A simple teaching aid for clinicians and students. Ann Epidemiol. 2005; 15, 421423.
27. Rothman, KJ, Gallacher, JE, Hatch, EE. Why representativeness should be avoided. Int J Epidemiol. 2013; 42, 10121014.
28. Van Lieshout, RJ, Boyle, MH, Saigal, S, Morrison, K, Schmidt, LA. Mental health of extremely low birth weight survivors in their 30s. Pediatrics. 2015; 135, 452459.
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Journal of Developmental Origins of Health and Disease
  • ISSN: 2040-1744
  • EISSN: 2040-1752
  • URL: /core/journals/journal-of-developmental-origins-of-health-and-disease
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