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Early life nutrition and the opportunity to influence long-term health: an Australasian perspective

Published online by Cambridge University Press:  26 January 2016

P. S. W. Davies*
Affiliation:
School of Medicine, Children’s Nutrition Research Centre, University of Queensland, Herston, Queensland, Australia
J. Funder
Affiliation:
The Hudson Institute of Medical Research, Clayton, Victoria, Australia
D. J. Palmer
Affiliation:
School of Paediatrics and Child Health, University of Western Australia, Perth, Australia
J. Sinn
Affiliation:
Department of Obstetric and Gynaecology and Neonatology, University of Sydney, Australia
M. H. Vickers
Affiliation:
Liggins Institute and Gravida: National Centre for Growth and Development, University of Auckland, Auckland, New Zealand
C. R. Wall
Affiliation:
Discipline of Nutrition and Dietetics, University of Auckland, New Zealand
*
*Address for correspondence: P. S.W. Davies, School of Medicine, Children’s Nutrition Research Centre, University of Queensland, Herston, QLD, Australia. (Email ps.davies@uq.edu.au)

Abstract

There are now significant data to support the hypothesis that early life nutrition in the fetus, infant and young child can have profound effects on long-term health. This review considers some of this evidence with specific reference to the current burden of disease in Australia and New Zealand. As the findings of further research become available, recommendations on optimizing early life nutrition should be formulated and made widely available as part of the preventative health policy agenda in both Australia and New Zealand.

Type
Review
Copyright
© Cambridge University Press and the International Society for Developmental Origins of Health and Disease 2016 

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References

1. Jang, H, Serra, C. Nutrition, epigenetics and diseases. Clin Nutr Res. 2014; 3, 18.Google Scholar
2. Singhal, A. The global epidemic of noncommunicable disease: the role of early-life factors. Nestle Nutr Inst Workshop Ser. 2014; 78, 123132.Google Scholar
3. Bammann, K, Peplies, J, De Henauw, S, et al. Early life course risk factors for childhood obesity: the IDEFICS case-control study. PLoS One. 2014; 9, 17.Google Scholar
4. Roseboom, T, van der Meulen, JHP, Osmond, C, et al. Coronary heart disease after prenatal exposure to the Dutch famine, 1944–45. Heart. 2000; 84, 595598.CrossRefGoogle Scholar
5. Roseboom, T, de Rooij, S, Painter, R. The Dutch famine and its long-term consequences for adult health. Early Hum Dev. 2006; 82, 485491.Google Scholar
6. Painter, RC, de Rooij, SR, Bossuyt, PM, et al. Early onset of coronary artery disease after prenatal exposure to the Dutch famine. Am J Clin Nutr. 2006; 84, 322327.Google Scholar
7. Eriksson, JG. Epidemiology, genes and the environment: lessons learned from the Helsinki Birth Cohort Study. J Intern Med. 2007; 261, 418425.Google Scholar
8. Prescott, S, Saffery, R. The role of epigenetic dysregulation in the epidemic of allergic disease. Clin Epigenetics. 2011; 2, 223232.Google Scholar
9. Golding, J. The Avon Longitudinal Study of Parents and Children (ALSPAC) – study design and collaborative opportunities. Eur J Endocrinol. 2004; 151, U119U123.Google Scholar
10. Lawlor, DA, Cooper, AR, Bain, C, et al. Associations of birth size and duration of breast feeding with cardiovascular fitness in childhood: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC). Eur J Epidemiol. 2008; 23, 411422.Google Scholar
11. Gaillard, R, Steegers, EAP, Franco, OH, Hofman, A, Jaddoe, VWV. Maternal weights gain in different periods of pregnancy and childhood cardio-metabolic outcomes. The Generation R Study. Int J Obes. 2015; 39, 677685.Google Scholar
12. Jaddoe, VWV, van Dujin, CM, Franco, OH, et al. The Generation R Study. Design and cohort update 2012. Eur J Epidemiol. 2012; 27, 739756.Google Scholar
13. Langley-Evans, SC. Nutrition in early life and the programming of adult disease: a review. J Hum Nutr Diet. 2015; 28(Suppl. 1), 114.Google Scholar
14. Royal Australian and New Zealand College of Obstetricians and Gynaecologists. Pre-pregnancy Counselling. College Statement C-Obs 3 (a). Current: November 2012.Google Scholar
15. Robker, RL. Evidence that obesity alters the quality of oocytes and embryos. Pathophysiology. 2008; 15, 115121.Google Scholar
16. Australian Institute of Health and Welfare. Obesity, 2014. Retrieved December 2014 from http://www.aihw.gov.au/overweight-and-obesity/ Google Scholar
17. Ministry of Health New Zealand Survey. Obesity key facts and statistics, 2012/2013. Retrieved December 2014 from http://www.health.govt.nz/our-work/diseases-and-conditions/obesity/obesity-key-facts-and-statistics Google Scholar
18. Torloni, AP., Betrán, BL, Horta, MU, et al. Prepregnancy BMI and the risk of gestational diabetes: a systematic review of the literature with meta-analysis. Obes Rev. 2009; 10, 194203.CrossRefGoogle ScholarPubMed
19. Bakos, HW, Henshaw, RC, Mitchell, M, Lane, M. Paternal body mass index is associated with decreased blastocyst development and reduced live birth rates following assisted reproductive technology. Fertil Steril. 2011; 95, 17001704.Google Scholar
20. Keltz, J, Zapantis, A, Jindal, SK, et al. Overweight men: clinical pregnancy after ART is decreased in IVF but not in ICSI cycles. J Assist Reprod Genet. 2010; 27, 539544.Google Scholar
21. Nguyen, RH, Wilcox, AJ, Skjaerven, R, Baird, DD. Men’s body mass index and infertility. Hum Reprod. 2007; 22, 24882493.Google Scholar
22. Ramlau-Hansen, CH, Thulstrup, AM, Nohr, EA, et al. Subfecundity in overweight and obese couples. Hum Reprod. 2007; 22, 16341637.Google Scholar
23. Veenendaal, MVE, Painter, RC, de Rooij, SR, et al. Transgenerational effects of prenatal exposure to the 1944–45 Dutch famine. BJOG. 2013; 120, 548554.Google Scholar
24. Ng, SF, Lin, RC, Laybutt, DR, et al. Chronic high-fat diet in fathers programs beta-cell dysfunction in female rat offspring. Nature. 2010; 467, 963966.Google Scholar
25. Lambrot, RI, Xu, C, Saint-Phar, S, et al. Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes. Nat Commun. 2013; 4, 2889.Google Scholar
26. de Rooij, SR, Painter, RC, Roseboom, TJ, et al. Glucose tolerance at age 58 and the decline of glucose tolerance in comparison with age 50 in people prenatally exposed to the Dutch famine. Diabetologia. 2006; 49, 637643.Google Scholar
27. Ravelli, ACJ, van der Meulen, JHP, Osmond, C, et al. Obesity at the age of 50 y in men and women exposed to famine prenatally. Am J Clin Nutr. 1999; 70, 811816.Google Scholar
28. Painter, RC, Osmond, C, Gluckman, P, et al. Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life. BJOG. 2008; 115, 12431249.Google Scholar
29. Bateson, P, Gluckman, PD, Hanson, M. The biology of developmental plasticity and the redictive adaptive response. J Physiol. 2014; 592(11), 23572368.Google Scholar
30. Waterland, RA. Epigenetic mechanisms affecting regulation of energy balance: many questions, few answers. Annu Rev Nutr. 2014; 34, 337355.Google Scholar
31. Gluckman, PD, Lillycrop, KA, Vickers, MH, et al. Metabolic plasticity during mammalian development is directionally dependent on early nutritional status. Proc Natl Acad Sci USA. 2007; 104, 1279612800.Google Scholar
32. Gluckman, PD, Hanson, MA, Cooper, C, Thornburg, KL. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med. 2008; 359, 6173.Google Scholar
33. Heindel, JJ, vom Saal, FS. Role of nutrition and environmental endocrine disrupting chemicals during the perinatal period on the aetiology of obesity. Mol Cell Endocrinol. 2009; 304, 9096.Google Scholar
34. Howe, LD, Ellison-Loschmann, L, Pearce, N, et al. Ethnic differences in risk factors for obesity in New Zealand infants. J Epidemiol Community Health. 2015; 69, 516522.Google Scholar
35. Kim, SY, Sharma, AJ, Sappenfield, W, et al. Association of maternal body mass index, excessive weight gain, and gestational diabetes mellitus with large-for-gestational-age births. Obstet Gynecol. 2014; 123, 737744.Google Scholar
36. Dodd, JM. Dietary and lifestyle advice for pregnant woman who are overweight or obese: the LIMIT randomised trial. Ann Nutr Metab. 2014; 64, 197202.Google Scholar
37. Institute of Medicine. Weight gain during pregnancy: re examining the guidelines. 2009. National Academies Press: Washington, DC.Google Scholar
38. de Jersey, SJ, Nicholson, JM, Callaway, LK, Daniels, LA. A prospective study of pregnancy weight gain in Australian women. Aust N Z J Obstet Gynaecol. 2012; 52, 545551.Google Scholar
39. Hure, AJ, Collins, CE, Giles, WB, Paul, JW, Smith, R. Greater maternal weight gain during pregnancy predicts a large but lean fetal phenotype: a prospective study. Matern Child Health J. 2012; 16, 13741384.Google Scholar
40. Fieldwick, D, Peterson, H, Stephen, M, et al. Management of excess weight in pregnancy in Otago, New Zealand: a qualitative study with lead maternity cares. N Z Med J. 2014; 127(1392), 2737.Google Scholar
41. Crozier, SR, Inskip, HM, Godfrey, KM, et al. Weight gain in pregnancy and childhood body composition: findings from the Southampton Women’s Survey. Am J Clin Nutr. 2010; 91, 17451751.Google Scholar
42. Davenport, MH, Ruchat, S-M, Giroux, I, et al. Timing of excessive pregnancy-related weight gain and offspring adiposity at birth. Obstet Gynecol. 2013; 122, 255261.Google Scholar
43. Chamberlain, C, Banks, E, Joshy, G, et al. Prevalence of gestational diabetes mellitus among Indigenous women and comparison with non Indigenous Australian women: 1990-2009. Aust N Z J Obstet Gynaecol. 2014; 54, 433440.Google Scholar
44. Ministry of Health New Zealand. Diabetes, 2013. Retrieved December 2014 from https://www.health.govt.nz/your-health/conditions-and-treatments/diseases-and-illnesses/diabetes.Google Scholar
45. Mitanchez, D, Yzydorczyk, C, Siddeek, B, et al. The offspring of the diabetic mother – short and long term implications. Best Pract Res Clin Obstet Gynaecol. 2015; 29, 256269.Google Scholar
46. Lawlor, DA, Lichtenstein, P, Langstrom, N. Association of maternal diabetes mellitus in pregnancy with offspring adiposity into early adulthood: sibling study in a prospective cohort of 280 866 men from 248 293 families. Circulation. 2011; 123, 258265.Google Scholar
47. Leng, J, Li, W, Zhang, S, et al. GDM womens pre-pregnancy overweight/obesity and gestational weight gain on offspring overweight status. PLoS One. 2015; 10, 115.Google Scholar
48. Yessoufou, A, Moutairou, K. Maternal diabetes in pregnancy: early and long-term outcomes on the offspring and the concept of ‘metabolic memory’. Exp Diabetes Res. 2011; 112.Google Scholar
49. Pereria, TJ, Fonseca, MA, Campbell, KE, et al. Maternal obesity characterized by gestational diabetes increases the susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome. J Physiol. 2015; 14, 31813197.Google Scholar
50. Hohwü, L, Li, J, Olsen, J, Sørensen, TI, Obel, C. Severe maternal stress exposure due to bereavement before, during and after pregnancy and risk of overweight and obesity in young adult men: a Danish national cohort study. PLoS One. 2014; 9, e97490.Google Scholar
51. Godfrey, KM, Sheppard, A, Gluckman, PD, et al. Epigenetic gene promoter methylation at birth is associated with child’s later adiposity. Diabetes. 2011; 60, 15281534.Google Scholar
52. Gardosi, J. Intrauterine growth restriction: new standards for assessing adverse outcome. Best Pract Res Clin Obstet Gynaecol. 2009; 23, 741749.Google Scholar
53. Osmond, C, Barker, DJ, Winter, PD, et al. Early growth and death from cardiovascular disease in women. BMJ. 1993; 307, 15191524.Google Scholar
54. Gluckman, PD, Hanson, MA. Living with the past: evolution, development, and patterns of disease. Science. 2004; 305, 17331736.Google Scholar
55. Gluckman, PD, Hanson, MA, Low, FM. The role of developmental plasticity and epigenetics in human health. Birth Defects Res C Embryo Today. 2011; 93, 1218.Google Scholar
56. Eriksson, JG, Forsen, T, Tuomilehto, J, et al. Early growth, adult income, and risk of stroke. Stroke. 2000; 31, 869874.Google Scholar
57. Osmond, C, Kajantie, E, Forsen, TJ, et al. Infant growth and stroke in adult life. The Helsinki birth cohort study. Stroke. 2007; 38, 264270.CrossRefGoogle ScholarPubMed
58. Curhan, GC, Chertow, GM, Willett, WC, et al. Birth weight and adult hypertension and obesity in women. Circulation. 1996; 94, 13101315.Google Scholar
59. Barker, DJP, Osmond, C, Winter, PD, Margetts, B, Simmonds, SJ. Weight in infancy and death from ischaemic heart disease. Lancet. 1989; 2, 577580.Google Scholar
60. Anderson, NH, Sadler, LC, Stewart, AW, et al. Independent risk factors for infants who are small for gestational age by customised birthweight centiles in a multi-ethnic New Zealand population. Aust N Z J Obstet Gynaecol. 2013; 53, 136142.Google Scholar
61. Mark, PJ, Sisala, C, Connor, K, et al. A maternal high fat diet in rat pregnancy reduces growth of the fetus and the placental junctional zone, but not placental labyrinth zone growth. J Dev Orig Health Dis. 2011; 2(1), 6370.Google Scholar
62. Brion, M-J, Ness, AR, Rogers, I, et al. Maternal macronutrient and energy intakes in pregnancy and offspring intake at 10 y: exploring parental comparisons and prenatal effects. Am J Clin Nutr. 2010; 91, 748756.Google Scholar
63. Lussana, F, Painter, RC, Ocke, MC, et al. Prenatal exposure to the Dutch famine is associated with a preference for fatty foods and a more atherogenic lipid profile. Am J Clin Nutr. 2008; 88(6), 16481652.CrossRefGoogle Scholar
64. Gugusheff, JR, Ong, ZY, Muhlhauser, BS. The early origins of food preferences: targeting the critical windows of development. FASEB. 2015; 29, 365373.Google Scholar
65. Langley-Evans, SC, Bellinger, L, McMullen, S. Animal models of programming: early life influences on appetite and feeding behaviour. Matern Child Nutr. 2005; 1, 142148.Google Scholar
66. Vickers, MH, Breier, BH, Cutfield, WS, Hoffman, PC, Gluckman, PD. Fetal origins of hyperphagia, obesity and hypertension and postnatal amplification of hypercaloric nutrition. Am J Physiol. 2000; 279(1), E83E87.Google Scholar
67. Prescott, S, Allen, KJ. Food allergy: riding the second wave of the allergy epidemic. Pediatr Allergy Immunol. 2011; 22, 155160.Google Scholar
68 Mullins, RJ. Paediatric food allergy trends in a community based specialist allergy practice. Med J Aus. 2007; 186, 618621.CrossRefGoogle Scholar
70. Prescott, SL. Early origins of allergic disease: a review of processes and influences during early immune development. Curr Opin Allergy Clin Immunol. 2003; 3, 125132.Google Scholar
71. Prescott, SL, Clifton, VL. Asthma and pregnancy: emerging evidence of epigenetic interactions in utero. Curr Opin Allergy Clin Immunol. 2009; 9, 417426.Google Scholar
72. Australian Bureau of Statistics/Food Standards Australia New Zealand. Australian Health Survey: usual nutrient intakes, Commonwealth of Australia, 2011-12 4364.0.55.008. 2015.Google Scholar
73. Sausenthaler, S, Heinrish, J, Koletzko, S, for the GINIplus and LISDA plus study groups. Early diet and the risk of allergy: what can we learn from the prospective birth cohort studies GINIplus and LISAplus? Am J Clin Nutr. 2011; 94, 212S217S.Google Scholar
74. Azad, MB, Konya, T, Maughan, H, et al. Gut microbiota of healthy Canadian & infants: profiles by mode of delivery and infant diet at 4 months. CMAJ. 2013; 185, 385394.Google Scholar
75. Kolokotroni, O, Middleton, N, Gavatha, M, et al. Asthma and atopy in children born by caesarean section: effect modification by family history of allergies: a population based cross-sectional study. BMC Pediatr. 2012; 12, 179.Google Scholar
76. Abrahamsson, TR, Jakobsson, HE, Andersson, AF, et al. Low diversity of the gut microbiota in infants with atopic eczema. J Allergy Clin Immunol. 2012; 129, 434440.Google Scholar
77. Ismail, IH, Oppedisano, F, Joseph, SJ, et al. Reduced gut microbial diversity in early life is associated with later development of eczema but not atopy in high-risk infants. Pediatr Allergy Immunol. 2012; 23, 674681.Google Scholar
78. Pike, KC, Crozier, SR, Lucas, JSA, et al. Patterns of fetal and infant growth are related to atopy and wheezing disorders at age 3 years. Thorax. 2010; 65, 10991106.CrossRefGoogle ScholarPubMed
79. Utsugi, M, Dobashi, K, Ishizuka, T, et al. c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production. J Immunol. 2003; 171, 628635.Google Scholar
80. Devereux, G, Turner, SW, Craig, LC, et al. Low maternal vitamin E intake during pregnancy is associated with asthma in 5-year-old children. Am J Respir Crit Care Med. 2006; 174, 499507.Google Scholar
81. Martindale, S, McNeill, G, Devereux, G, et al. Antioxidant intake in pregnancy in relation to wheeze and eczema in the first two years of life. Am J Respir Crit Care Med. 2005; 171, 121128.Google Scholar
82. Dunstan, JA, Mori, TA, Barden, A, et al. Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: a randomized, controlled trial. J Allergy Clin Immunol. 2003; 112, 11781184.Google Scholar
83. Palmer, DJ, Sullivan, T, Gold, MS, et al. Effect of n-3 long chain polyunsaturated fatty acids (LCPUFA) supplementation in pregnancy on infant allergies in the first year of life: a randomised controlled trial. BMJ. 2012; 344, e184.Google Scholar
84. Prescott, SL, Barden, AE, Mori, TA, Dunstan, JA. Maternal fish oil supplementation in pregnancy modifies neonatal leukotriene production by cord-blood-derived neutrophils. Clin Sci. 2007; 113, 409416.Google Scholar
85. Innis, SM. Metabolic programming of long-term outcomes due to fatty acid nutrition in early life. Matern Child Nutr. 2011; 7(Suppl. 2), 112123.Google Scholar
86. Forsyth, JS, Willatts, P, Agostoni, C, et al. Long chain polyunsaturated fatty acid supplementation in infant formula and blood pressure in later childhood: follow up of a randomised controlled trial. BMJ. 2003; 326, 953.Google Scholar
87. Skilton, MR, Ayer, JG, Harmer, JA, et al. Impaired fetal growth and arterial wall thickening: a randomized trial of omega-3 supplementation. Pediatrics. 2012; 29, e698e703.Google Scholar
88. Kimlin, M. Geographic location and vitamin D synthesis. Mol Aspects Med. 2008; 29, 453461.Google Scholar
89. Camargo, CAJ, Clark, S, Kaplan, MS, et al. Regional differences in EpiPen prescriptions in the United States: the potential role of vitamin D. J Allergy Clin Immunol. 2007; 120, 131136.Google Scholar
90. Weiland, SK, Husing, A, Strachan, DP, et al. Climate and the prevalence of symptoms of asthma and atopic eczema in children.. Occup Environ Med. 2004; 61, 609615.Google Scholar
91. Krstic, G. Asthma prevalence associated with geographical latitude and regional insolation in the United States of America and Australia. PLoS One. 2011; 6, e18492.Google Scholar
92. Aghajafari, F, Nagulesapillai, T, Ronksley, PE, et al. Association between maternal serum 25-hydroxyvitamin D level and pregnany and neonatal outcomes: systematic review and meta analysis of observational studies. BMJ. 2013; 346, f1169.Google Scholar
93. Jones, AP, Palmer, D, Zhang, G, Prescott, SL. Cord blood 25-hydroxyvitamin D3 and allergic disease during infancy. Pediatrics. 2012; 130, e1128e1135.Google Scholar
94. Savendahl, L. Vitamin D deficiency during pregnancy-potential threat to the child. Acta Paediatr. 2011; 100, 484485.Google Scholar
95. Gill, TK, Hill, CL, Shanahan, EM, et al. Vitamin D levels in an Australian population. BMC Public Health. 2014; 14, 1001.CrossRefGoogle Scholar
96. Cordain, L, Eaton, SB, Sebastian, A, et al. Origins and evolution of the Western diet: health implications for the 21st century. Am J Clin Nutr. 2005; 81, 341354.Google Scholar
97. Kuhnlein, HV, Receveur, O. Dietary change and traditional food systems of indigenous peoples. Annu Rev Nutr. 1996; 16, 417442.Google Scholar
98. Renz, H, Brandtzaeg, P, Hornef, M. The impact of perinatal immune development on mucosal homeostasis and chronic inflammation. Nat Rev Immunol. 2012; 12, 923.Google Scholar
99. Rautava, S, Luoto, R, Salminen, S, et al. Microbial contact during pregnancy, intestinal colonization and human disease. Nat Rev Gastroenterol Hepatol. 2012; 9, 565576.Google Scholar
100. Nauta, AJ, Ben Amor, K, Knol, J, et al. Relevance of pre- and postnatal nutrition to development and interplay between the microbiota and metabolic and immune systems. Am J Clin Nutr. 2013; 98, 586S593S.Google Scholar
101. Nylund, L, Satokari, R, Nikkila, J, et al. Microarray analysis reveals marked intestinal microbiota aberrancy in infants having eczema compared to healthy children in at-risk for atopic disease. BMC Microbiol. 2013; 13, 12.Google Scholar
102. Renz, H. Development and regulation of immune responses in pre- and postnatal life. Clin Biochem. 2011; 44, 495.Google Scholar
103. Sudo, N, Sawamura, S, Tanaka, K, et al. The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol. 1997; 159, 17391745.Google Scholar
104. Turnbaugh, PJ, Ley, RE, Mahowald, MA, et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature. 2006; 444, 10271031.Google Scholar
105. van Hoffen, E, Ruiter, B, Faber, J, et al. A specific mixture of short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides induces a beneficial immunoglobulin profile in infants at high risk for allergy. Allergy. 2009; 64, 484487.Google Scholar
106. Cani, PD, Possemiers, S, Van de Wiele, T, et al. Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut. 2009; 58, 10911103.Google Scholar
107. Dogaru, CM, Nyffenegger, D, Pescatore, AM, et al. Breastfeeding and Childhood Asthma: Systematic Review and Meta-Analysis. Am J Epidemiol. 2014; 179, 11531169.Google Scholar
108. Arenz, S, Ruckerl, R, Koletzko, B, et al. Breast-feeding and childhood obesity – a systematic review. Int J Obes. 2004; 28, 12471256.Google Scholar
109. Kramer, MS, Aboud, F, Mironova, E, et al. Breastfeeding and child cognitive development: new evidence from a large randomized trial. Arch Gen Psychiatry. 2008; 65, 578584.Google Scholar
110. National Health and Medical Research Council. Infant Feeding Guidelines. 2012. National Health and Medical Research Council: Canberra.Google Scholar
111. Du Toit, G, Katz, Y, Sasieni, P, et al. Early consumption of peanuts in infancy is associated with a low prevalence of peanut allergy. J Allergy Clin Immunol. 2008; 122, 984991.Google Scholar
112. Prescott, SL, Smith, P, Tang, M, et al. The importance of early complementary feeding in the development of oral tolerance: concerns and controversies. Pediatr Allergy Immunol. 2008; 19, 375380.Google Scholar
113. Koplin, JJ, Osborne, NJ, Wake, M, et al. Can early introduction of egg prevent egg allergy in infants? A population-based study. J Allergy Clin Immunol. 2010; 126, 807813.Google Scholar
114. Australasian Society of Clinical Immunology and Allergy. Infant feeding advice, 2010. Retrieved December 2014 from www.allergy.org.au/content/view/350/287.Google Scholar
115. Pearce, J, Taylor, MA, Langley-Evans, SC. Timing of the introduction of complementary feeding and risk of childhood obesity: a systematic review. Int J Obes. 2013; 37, 12951306.Google Scholar
116. Daniels, L, Mallan, KM, Fildes, A, Wilson, J. The timing of solid introduction in an obesogenic environment: a narrative review of the evidence and methodological issues. Aust N Z J Public Health 2015; 39, 366373.Google Scholar
117. Newby, R, Davies, PSW. Introduction of complementary foods in contemporary Australian infants: what, when and why. J Paediatr Child Health. 2015; 51(2), 186191.Google Scholar
118. Weber, M, Grote, V, Closa-Monasterolo, R, et al. Lower protein content in infant formula reduces BMI and obesity risk at school age: follow-up of a randomized trial. Am J Clin Nutr. 2014; 99, 10411051.Google Scholar
119. Hörnell, A, Lagström, H, Lande, B, Thorsdottir, I. Protein intake from 0 to 18 years of age and its relation to health: a systematic literature review for the 5th Nordic Nutrition Recommendations. Food Nutr Res. 2013; 57, 142.Google Scholar
120. Baird, J, Fisher, D, Lucas, P, et al. Being big or growing fast: systematic review of size and growth in infancy and later obesity. BMJ. 2005; 331, 929.Google Scholar
121. Monteiro, PO, Victora, CG. Rapid growth in infancy and childhood and obesity in later life – a systematic review. Obes Rev. 2005; 6, 143154.Google Scholar
122. Singal, A, Cole, TC, Fewtrell, M, Deanfield, J., Lucas, A. Is slower early growth beneficial for long term cardiovascular health? Circulation. 2004; 109, 11081113.Google Scholar
123. Ziegler, EE, Thureen, PJ, Carlson, SJ. Aggressive nutrition of the very low birthweight infant. Clin Perinatol. 2002; 29, 225244.Google Scholar
124. National Health and Medical Research Council. Clinical Practice Guidelines for the Management of Overweight and Obesity in Adults, Adolescents and Children in Australia. 2013. National Health and Medical Research Council: Melbourne.Google Scholar