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Circulating microfilariae in haematological malignancies: do they have a role in pathogenesis?

  • L.S. Kerketta (a1) and K. Ghosh (a1)

Abstract

Filariasis is very common in tropical countries. It is endemic in the coastal areas of India. We report four cases of haematological malignancy where peripheral blood and bone marrow smears did not show any microfilariae but conventional cytogenetic preparations from all the four cases showed the presence of parasites. Their morphology confirmed the diagnosis of all cases as bancroftian filariasis. Therefore all types of cytogenetic preparations should be screened carefully in the endemic areas along the coastal zones of India for the presence of this parasite.

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Present address: Surat Raktadan Kendra & Research Centre, Udhna Magdalla Road, Surat 395002, Gujrat, India.

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Arundhati, A., Kumar, A. & Kumar, R. (2011) Acute lymphoblastic leukemia with microfilaria: a rare coincidence in bone marrow aspirate. Indian Journal of Hematology & Blood Transfusion 27, 111112.
Cheesbrough, M. (2006) District laboratory practice in tropical countries. London, Churchill Livingstone.
Emmanuel, B., Kawira, E., Ogwang, M.D., Wabirga, H., Magatti, J., Nukruma, F., Neequaye, T., Bhatia, K., Brubaker, G., Biggar, R.J. & Mbulaiteye, S.M. (2011) African Burkitt's lymphoma: age specific risk and correlation with malaria biomarkers. American Journal of Tropical Medicine and Hygiene 84, 397401.
Gupta, K., Sehgal, A., Puri, M.M. & Sidhwa, H.K. (2002) Microfilaria in association with other diseases. A report of six cases. Acta Cytologica 46, 776778.
Gupta, S., Sodhani, P., Jain, S. & Kumar, N. (2001) Microfilariae in association with neoplastic lesion: report of five cases. Cytopathology 12, 120126.
Hoerauf, A., Satoguina, J., Saeftel, M. & Specht, S. (2005) Immunomodulation by filarial nematodes. Parasite Immunology 27, 417429.
Kerketta, L.S., Babu Rao, V. & Ghosh, K. (2012) Standard karyotyping concentrates microfilaria and can be a valid concentrating technique for their detection. Tropical Medicine & International Health 17, 12221226.
Nandkumar, A. (2001) National Cancer Registry Programme. Consolidated report of the population based cancer registries 1990–1996. Incidence and distribution of cancer. pp. 7073. Ansari Nagar, New Delhi, Indian Council of Medical Research.
Russel, S., Rao, A.R., Khamre, J.M., Praharaj, B.C. & Rao, C.K. (1980) Disappearance of some Brugia malayi foci from Madhya Pradesh, Orissa and Tamil Nadu and co-existence of Malayan and Bancroftian filariasis in some pockets. Journal of Communicable Diseases 12, 183187.
Sabesan, S., Vanamali, P., Raju, K.H.K. & Jambulingam, P. (2010) Lymphatic filariasis in India: epidemiology and control measures. Journal of Postgraduate Medicine 56, 232238.
Singh, S.K., Pujani, M. & Pujani, M. (2010) Microfilaria in malignant pleural effusion: an unusual association. Indian Journal of Medical Microbiology 28, 392394.
Tajima, K., Tominaga, S., Shimizu, H. & Suchi, T. (1981) A hypothesis on the etiology of adult T-cell leukemia/lymphoma. Japanese Journal of Cancer Research: Gann 72, 684691.
Weil, G.J., Lammie, P.J. & Weiss, N. (1997) The ICT filariasis test. A rapid-format antigen test for diagnosis of Bancroftian filariasis. Parasitology Today 13, 401404.

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