Skip to main content
×
×
Home

Cross protection against Taenia taeniaeformis in rats vaccinated with non-viable oncospheres of Asian Taenia or T. saginata

  • A. Ito (a1), P.C. Fan (a2), W.C. Chung (a3) and M. Suzuki (a4)
Abstract

It was determined to examine whether rats injected with non-viable oncospheres of Asian Taenia or Taenia saginata became resistant to challenge infection with eggs of Taenia taeniaeformis, since (a) metacestodes of Asian Taenia and T. taeniaeformis develop in the liver of pigs and rats, respectively, and (b) Asian Taenia and T. saginata have human origins. Rats injected intravenously or subcutaneously with complete Freund's adjuvant with non-viable oncospheres of Asian Taenia showed statistically significant resistance to challenge infection with eggs of T. taeniaeformis, whereas those injected with non-viable oncospheres of T. saginata did not show any resistance.

Copyright
References
Hide All
Chan, C.H., Fan, P.C., Chung, W.C., Chen, Y.A., Wu, C.C., Hsu, M.C. & Chao, D. (1987) Studies on taeniasis in Taiwan. I. Prevalence of taeniasis among aborigines in Wulai District, Taipei Country, Northern Taiwan. Proceedings of the 1st Sino-American Symposium on Biotechnology and Parasitic Diseases, 1, 6577.
Chung, W.C., Fan, P.C., Chan, C.H., Hsu, M.C. & Yu, Y.I. (1988) Studies on taeniasis in Taiwan. VII. Prevalence of taeniasis among Atayal aborigines in Tatung District, Ilan Country, Northeast Taiwan. Chinese Journal of Parasitology, 1, 152166.
Fan, P.C. (1988). Taiwan Taenia and taeniasis. Parasitology Today 4, 8688.
Fan, P.C., Chung, W.C., Lin, C.Y., Soh, C.T., Lee, K.T., Kosman, M.L., Kosin, E., Depari, A.A. & Napitupulu, T. (1988) Studies on taeniasis in Taiwan. VI. Is Taenia saginata from Taiwan, Korea, and Indonesia a new species? Chinese Journal of Parasitology 1, 5670.
Harrison, G.B.L., Heath, D.D., Dempster, R.P., Lawrence, S.B., Lightowlers, M.W. & Rickard, M.D. (1993) Identification of host-protective antigens of Taenia ovis oncospheres. International Journal for Parasitology 23, 4150.
Ito, A. (1992) Cysticercosis in Asian-Pacific Regions. Parasitology Today 8, 181182.
Ito, A. & Hashimoto, A. (1993) Vaccination with hatched but non-activated, non-viable oncospheres of Taenia taeniaeformis in rats. Journal of Helminthology 67, 165168.
Ito, A., Bøgh, H., Lightowlers, M.W. & Rickard, M.D. (1988) Cross-resistance between Taenia taeniaeformis and Hymenolepis nana infections in C3H/He mice. International Journal for Parasitology 18, 691694.
Ito, A., Onitake, K., Sasaki, J. & Takami, T. (1991a) Hymenolepis nana: Immunity against oncosphere challenge in mice previously given viable or non-viable oncospheres of H. nana, H. diminuta, H. microstoma and Taenia taeniaeformis. International Journal for Parasitology 21, 241245.
Ito, A., Bøgh, H., Lightowlers, M.W., Mitchell, G.F., Takami, T., Kamiya, M., Onitake, K. & Rickard, M.D. (1991b) Vaccination against Taenia taeniaeformis infection in rats using a recombinant protein and preliminary analysis of the induced antibody response. Molecular and Biochemical Parasitology 44, 4352.
Johnson, K.S., Harrison, G.B.L., Lightowlers, M.W., O'Hoy, K.L., Cougle, W.G., Dempster, R.P., Lawrence, S.B., Vinton, J.G., Heath, D.D. & Rickard, M.D. (1989) High level protection against a helminth parasite induced by a defined recombinant antigen. Nature 338, 585587.
Lightowlers, M.W., Mitchell, G.F., Bowtell, D.D.L., Anders, R.F. & Rickard, M.D. (1984) Immunisation against Taenia taeniaeformis in mice: studies on the characterisation of antigens from oncospheres. International Journal for Parasitology 14, 321333.
Lightowlers, M.W., Mitchell, G.F. & Rickard, M.D. (1993) Cestodes. pp. 438472in Warren, K.S. (Ed.) Immunology and molecular biology of parasitic infections. Oxford, Blackwell.
Onitake, K., Sasaki, J., Andreassen, J. & Ito, A. (1989) Hymenolepis microstoma oncospheres invade the intestinal tissue of the definitive host. Journal of Helminthology 69, 170172.
Thompson, R.C.A., Penhale, W.J., White, D.A. & Pass, D.A. (1982) BCG-induced inhibition and destruction of Taenia taeniaeformis in mice. Parasite Immunology 4, 9399.
Zarlenga, D.S., McManus, D.P., Fan, P.C. & Cross, J.H. (1991) Characterization and detection of a newly described Asian taeniid using cloned ribosomal DNA fragments and sequence amplification by the polymerase chain reaction. Experimental Parasitology 72, 174183.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Journal of Helminthology
  • ISSN: 0022-149X
  • EISSN: 1475-2697
  • URL: /core/journals/journal-of-helminthology
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 6 *
Loading metrics...

Abstract views

Total abstract views: 246 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 13th June 2018. This data will be updated every 24 hours.