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Studies with Brugia pahangi. 18. Anthelmintic effects of stibocaptate

  • D. A. Denham (a1), R. R. Suswillo (a1) and Rosemary Rogers (a1)
Abstract

Stibocaptate (Astiban, Hoffman - La Roche) killed third stage larvae of Brugia pahangi in vitro at 50 p.p.m. but had no effect on microfilariae at 1 × 104 p.p.m. No larvae developed in infected mosquitoes fed 1% stibocaptate in 10% sucrose. It was neither micro-nor macrofilaricidal in neither jirds or cats but did affect embryogenesis.

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Rogers, R. and Denham, D. A. (1976) Studies with Brugia pahangi. 12. The activity of levamisole. Journal of Helminthology, 50, 2128.
Rogers, R., Ellis, D. S. and Denham, D. A. (1976) Studies with Brugia pahangi. 14. Intrauterine development of the microfilaria and a comparison with other filarial species. Journal of Helminthology, 50, 251257.
Suswillo, R. R. and Denham, D. A. (1977) A new system of testing for filaricidal activity using transplanted adult Brugia in the jird. Journal of Parasitology, 63, 591592.
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Journal of Helminthology
  • ISSN: 0022-149X
  • EISSN: 1475-2697
  • URL: /core/journals/journal-of-helminthology
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