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    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.
    Chai, Jong-Yil 2013. Praziquantel Treatment in Trematode and Cestode Infections: An Update. Infection & Chemotherapy, Vol. 45, Issue. 1, p. 32.
    Reimschuessel, R Gieseker, C and Poynton, S 2011. In vitro effect of seven antiparasitics on Acolpenteron ureteroecetes (Dactylogyridae) from largemouth bass Micropterus salmoides (Centrarchidae). Diseases of Aquatic Organisms, Vol. 94, Issue. 1, p. 59.
    Sharma, Satyavan and Anand, Nitya 1997. Approaches to Design and Synthesis of Antiparasitic Drugs. Vol. 25, Issue. , p. 273.
    Ohnishi, Kenji and Murata, Misako 1994. Praziquantel for the treatment of Diphyllobothrium nihonkaiense infections in humans. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 88, Issue. 5, p. 580.
    Ohnishi, Kenji and Murata, Misako 1993. Single dose treatment with praziquantel for human Diphyllobothrium nihonkaiense infections. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 87, Issue. 4, p. 482.
    Singh, Sudhir K. and Sharma, Satyavan 1991. Current status of medicinal research in helminth diseases. Medicinal Research Reviews, Vol. 11, Issue. 6, p. 581.
    Groll, Erhard 1984. Vol. 20, Issue. , p. 219.
    Andrews, Peter Thomas, Herbert Pohlke, Rolf and Seubert, JÜRgen 1983. Praziquantel. Medicinal Research Reviews, Vol. 3, Issue. 2, p. 147.
    Rim, Han-Jong Lyu, Kwang-Sa Lee, Joon-Sang and Joo, Kyoung-Hwan 1981. Clinical evaluation of the therapeutic efficacy of praziquantel (Embay 8440) againstClonorchis sinensisinfection in man. Annals of Tropical Medicine & Parasitology, Vol. 75, Issue. 1, p. 27.
    Van den Bossche, Hugo 1980. Biology of the Tapeworm Hymenolepis Diminuta. p. 639.
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Tests with a new compound (Praziquantel) against Diphyllobothrium latum

  • G. Bylund (a1), B. Bång (a1) and K. Wikgren (a1)
Abstract

Praziquantel (Droncit) is a new anthelminthic agent with a strikingly wide therapeutic index. The efficiency of the drug against Diphyllobothrium latum was tested in vivo and in vitro. With a drug dose of 50 mg/kg, artificially infected hamsters were completely cured. The threshold value of the active dose was between 2·5 and 10·0 mg/kg. Clinical trials with Praziquantel against human diphyllobothriasis show great promise, all of ten patients treated with 25·0 mg/kg of the drug being cured. Praziquantel had little effect on larval or adult diphyllobothriids in vitro.

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COPYRIGHT: © Cambridge University Press 1977
References
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Rommel, M., Grelck, H. and Hörnchner, F. (1976) Zur Wirksamkeit von Praziquantel gegen Bandwürmer in experimentell infizierten Hunden und Katzen. Berliner und Münchener Tierärztliche Wochenschrift, 89, 255–257.
Thomas, H., Gönnert, R., Pohlke, R. and Seubert, J. (1975a) Experimental and clinical studies with a new compound against tapeworms. Paper read at the 2nd European Multi-Colloquy of Parasitology, Trogir, Yugoslavia, 1975, pp. 1–4.
Thomas, H., Gönnert, R., Pohlke, R. and Seubert, J. (1975b) Experience with a new compound against larval cestodes. Paper read at the 2nd European Multi-Colloquy of Parasitology, Trogir, Yugoslavia, 1975, pp. 1–4.
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Journal of Helminthology
  • ISSN: 0022-149X
  • EISSN: 1475-2697
  • URL: /core/journals/journal-of-helminthology
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