Hostname: page-component-8448b6f56d-c4f8m Total loading time: 0 Render date: 2024-04-18T13:34:39.277Z Has data issue: false hasContentIssue false
  • English
  • Français

The benefits of betahistine or vestibular rehabilitation (Tetrax biofeedback) on the quality of life and fall risk in patients with Ménière's disease

Published online by Cambridge University Press:  07 December 2020

J L Liu ,
J G Liu ,
X B Chen  and
Y H Liu
J L Liu
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, the Second Affiliated Hospital of Nanchang University, China
J G Liu
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, the Second Affiliated Hospital of Nanchang University, China
X B Chen
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, the Second Affiliated Hospital of Nanchang University, China
Y H Liu*
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, the Second Affiliated Hospital of Nanchang University, China
*
Author for correspondence: Prof Yuehui Liu, Department of Otolaryngology, Head and Neck Surgery, the Second Affiliated Hospital of Nanchang University, NO. 1 Minde Rd, Donghu District, Nanchang, 330006, China Email: liuyuehuiclark@21cn.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective

This study aimed to evaluate the benefits of betahistine or vestibular rehabilitation (Tetrax biofeedback) on the quality of life and fall risk in patients with Ménière's disease.

Methods

Sixty-six patients with Ménière's disease were randomly divided into three groups: betahistine, Tetrax and control groups. Patients’ Dizziness Handicap Index and Tetrax fall index scores were obtained before and after treatment.

Results

Patients in the betahistine and Tetrax groups showed significant improvements in Dizziness Handicap Index and fall index scores after treatment versus before treatment (p < 0.05). The improvements in the Tetrax group were significantly greater than those in the betahistine group (p < 0.05).

Conclusions

Betahistine and vestibular rehabilitation (Tetrax biofeedback) improve the quality of life and reduce the risk of falling in patients with Ménière's disease. Vestibular rehabilitation (Tetrax biofeedback) is an effective management method for Ménière's disease.

Keywords

Meniere's DiseaseBetahistineRehabilitation
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 134 , Issue 12 , December 2020 , pp. 1073 - 1076
Copyright
Copyright © JLO (1984) Limited, 2020

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Dr J Liu takes responsibility for the integrity of the content of the paper

References

Hallpike, CS, Cairns, H. Observations on the pathology of Méniere's syndrome: (section of otology). Proc R Soc Med 1938;31:1317–36Google Scholar
Gürkov, R, Flatz, W, Louza, J, Strupp, M, Krause, E. In vivo visualization of endolyphatic hydrops in patients with Meniere's disease: correlation with audiovestibular function. Eur Arch Otorhinolaryngol 2011;268:1743–8CrossRefGoogle ScholarPubMed
American Academy of Otolaryngology - Head and Neck Foundation. Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Menière's disease. Otolaryngol Head Neck Surg 1995;113:181–5CrossRefGoogle Scholar
Minor, LB, Schessel, DA, Carey, JP. Ménière's disease. Curr Opin Neurol 2004;17:9–16CrossRefGoogle ScholarPubMed
Fujimoto, C, Egami, N, Kinoshita, M, Sugasawa, K, Yamasoba, T, Iwasaki, S. Factors affecting postural instability in Meniere's disease. Otolaryngol Head Neck Surg 2013;149:759–65CrossRefGoogle ScholarPubMed
Nevoux, J, Barbara, M, Dornhoffer, J, Gibson, W, Kitahara, T, Darrouzet, V. International Consensus (ICON) on treatment of Ménière's disease. Eur Ann Otorhinolaryngol Head Neck Dis 2018;135:S29–32CrossRefGoogle ScholarPubMed
Magnan, J, Özgirgin, ON, Trabalzini, F, Lacour, M, Escamez, AL, Magnusson, M et al. European position statement on diagnosis, and treatment of Meniere's disease. J Int Adv Otol 2018;14:317–21CrossRefGoogle ScholarPubMed
Gorski, LP, da Silva, AM, Cusin, FS, Cesaroni, S, Ganança, MM, Caovilla, HH. Body balance at static posturography in vestibular migraine. Braz J Otorhinolaryngol 2019;85:183–92CrossRefGoogle ScholarPubMed
Jacobson, GP, Newman, CW. The development of the Dizziness Handicap Inventory. Arch Otolaryngol Head Neck Surg 1990;116:424–7CrossRefGoogle ScholarPubMed
Song, YB, Chun, MH, Kim, W, Lee, SJ, Yi, JH, Park, DH. The effect of virtual reality and tetra-ataxiometric posturography programs on stroke patients with impaired standing balance. Ann Rehabil Med 2014;38:160–6CrossRefGoogle ScholarPubMed
Quitschal, RM, Fukunaga, JY, Ganança, MM, Caovilla, HH. Evaluation of postural control in unilateral vestibular hypofunction. Braz J Otorhinolaryngol 2014;80:339–45CrossRefGoogle ScholarPubMed
Pothula, VB, Chew, F, Lesser, THJ, Sharma, AK. Falls and vestibular impairment. Clin Otolaryngol Allied Sci 2004;29:179–82CrossRefGoogle ScholarPubMed
Lacour, M, van de Heyning, PH, Novotny, M, Tighilet, B. Betahistine in the treatment of Ménière's disease. Neuropsychiatr Dis Treat 2007;3:429–40Google ScholarPubMed
Casani, AP, Guidetti, G, Schoenhuber, R, Consensus Conference Group. Report from a Consensus Conference on the treatment of Ménière's disease with betahistine: rationale, methodology and results. Acta Otorhinolaryngol Ital 2018;38:460–7Google ScholarPubMed
Nauta, JJ. Meta-analysis of clinical studies with betahistine in Ménière's disease and vestibular vertigo. Eur Arch Otorhinolaryngol 2014;271:887–97CrossRefGoogle ScholarPubMed
Adrion, C, Fischer, CS, Wagner, J, Gürkov, R, Mansmann, U, Strupp, M et al. Efficacy and safety of betahistine treatment in patients with Meniere's disease: primary results of a long term, multicentre, double blind, randomised, placebo controlled, dose defining trial (BEMED trial). BMJ 2016;352:h6816CrossRefGoogle Scholar
Murdin, L, Hussain, K, Schilder, AG. Betahistine for symptoms of vertigo. Cochrane Database Syst Rev 2016;(6):CD010696Google Scholar
Hsu, SY, Fang, TY, Yeh, SC, Su, MC, Wang, PC, Wang, VY. Three-dimensional, virtual reality vestibular rehabilitation for chronic imbalance problem caused by Ménière's disease: a pilot study. Disabil Rehabil 2017;39:1601–6CrossRefGoogle ScholarPubMed
Hillier, SL, McDonnell, M. Vestibular rehabilitation for unilateral peripheral vestibular dysfunction. Clin Otolaryngol 2011;36:248–9CrossRefGoogle ScholarPubMed
Horning, E, Gorman, S. Vestibular rehabilitation decreases fall risk and improves gaze stability for an older individual with unilateral vestibular hypofunction. J Geriatr Phys Ther 2007;30:121–7CrossRefGoogle ScholarPubMed
Gottshall, KR, Hoffer, ME, Moore, RJ, Balough, BJ. The role of vestibular rehabilitation in the treatment of Meniere's disease. Otolaryngol Head Neck Surg 2005;133:326–8CrossRefGoogle ScholarPubMed
McDonnell, MN, Hillier, SL. Vestibular rehabilitation for unilateral peripheral vestibular dysfunction. Cochrane Database Syst Rev 2015;(1):CD005397Google ScholarPubMed
Yeh, SC, Chen, S, Wang, PC, Su, MC, Chang, CH, Tsai, PY. Interactive 3-dimensional virtual reality rehabilitation for patients with chronic imbalance and vestibular dysfunction. Technol Health Care 2014;22:915–21CrossRefGoogle ScholarPubMed