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Ciliary beat frequency of human middle-ear mucosa measured in vitro

Published online by Cambridge University Press:  29 June 2007

Y. Roth
Affiliation:
From the Department of Polymer Research, The Weizmann Institute of Science, Rehovot, and Department of Otolaryngology, Hillel Jaffe Memorial Hospital, Hadera, Israel.
E. Ostfeld*
Affiliation:
From the Department of Polymer Research, The Weizmann Institute of Science, Rehovot, and Department of Otolaryngology, Hillel Jaffe Memorial Hospital, Hadera, Israel.
*
E. Ostfeld, M.D., Otolaryngology, Hillel Jaffe Memorial Hospital, Haders 38100. Israel.

Abstract

Brush biopsies from the middle-ear (ME) and nasal mucosa were taken from a 4-year-old girl with complete situs inversus, recurrent otitis media and tonsillitis, who underwent tonsillectomy, adenoidectomy and bilateral myringotomy with insertion of ventilation tubes. Ciliary beat frequencies (CBF, Hz.) of the ME and nasal samples, measured by a photoelectric system equipped with a fiber-optic probe, were 9.5 Hz. (±1.2) and 13.7 Hz. (±4.1) respectively. These values are similar to CBF of nasal samples obtained from normal subjects. In vitro CBF assessment is a useful investigative tool for the study of mucociliary activity in the ME, as in patients suspected to have ciliary dyskinesia syndrome.

Type
Research Article
Copyright
Copyright © JLO (1984) Limited 1984

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References

Baum, G. L., Roth, Y., Teichtahl, H., Aharonson, E., and Priel, Z. (1982) Ciliary beat frequency of respiratory mucosal cells; comparison of nasal and tracheal sampling sites. American Review of Respiratory Diseases, Supplement 125: 244.Google Scholar
Dulfano, M. J., Luk, C. K., Beckage, M., and Wooten, O. (1981) Ciliary beat frequency in human respiratory explants. American Review of Respiratory Diseases, 123: 139140.Google ScholarPubMed
Elbrønd, O., and Larsen, E. (1976) Mucociliary function of the Eustachian tube: assessment by saccharine test in patients with dry perforations of the tympanic membrane. Archives of Otolaryngology, 102: 539541.CrossRefGoogle Scholar
Hadas, E., and Sadé, J. (1979) Clearance by the mucociliary system in ‘simple chronic otitis media’. Journal of Laryngology and Otology, 93: 781783.CrossRefGoogle ScholarPubMed
Jahrsdoerfer, R., Feldman, P. S., Rubel, E. W., Guerrant, J. L., Eggleston, P. A., and Selden, R. F. (1979) Otitis media and the immotile cilia syndrome. The Laryngoscope, 89: 769777.CrossRefGoogle ScholarPubMed
Kawabata, I. (1981) Surface structure of the human middle ear. with special reference to the mastoid cavity. Biomedical Research, Supplement 2: 433436.Google Scholar
Kenndy, J. R., and Duckett, K. E. (1981) The study of ciliary frequencies with an optical spectrum analysis system. Experimental Cell Research, 135: 147156.CrossRefGoogle Scholar
Konieizko, N., Nakhosteen, J. A., Mizera, W., Kasparek, R., and Hesse, H. (1981) Ciliary beat frequency of biopsy samples taken from normal persons and patients with various lung diseases. xvChest, 80: 855857.Google Scholar
Lim, D. J. (1979) Normal and pathological mucosa of the middle ear and Eustachian tube. Clinical Otolaryngology, 4: 213234.CrossRefGoogle ScholarPubMed
Pedersen, M., Morkassel, E., Nielsen, M. H., and Mygind, N. (1981) Kartagener's syndrome: preliminary report on cilia structure, function and upper airway symptoms. Chest. 80: 858860.CrossRefGoogle ScholarPubMed
Reimer, A., Mecklenburg, C. V., and Toremalm, N. G: (1978) The mucociliary activity of the upper respiratory tract. III. A functional and morphological study on human and animal material with special reference to maxillary sinus diseases. Acta Otolaryngologica, Supplement 355.CrossRefGoogle Scholar
Rossman, C. M., Forrest, J. B., Lee, R. M. K. W., Newhouse, A. F., and Newhouse, M. T. (1981) The dyskinetic cilia syndrome. Chest, 8: 860865.Google Scholar
Rutland, J., and Cole, P. J. (1980) Non-invasive sampling of nasal cilia for measurement of beat frequency and study of ultrastructure. The Lancet, 2: 564565.CrossRefGoogle ScholarPubMed
Rutland, J., and Cole, P. J. (1981) Nasal mucociliary clearance and ciliary beat frequency in cystic fibrosis compared with sinusitis and bronchiectasis. Thorax, 36: 654658.CrossRefGoogle ScholarPubMed
Rutland, J., Griffin, W. M., and Cole, P. J. (1982) Human ciliary beat frequency in epithelium from intathoracic and extrathoracic airways. American Review of Respiratory Diseases, 125: 100105.Google Scholar
Sadé, J. (1967) Ciliary activity and middle ear clearance. Archives of Otolaryngology, 86: 128135.CrossRefGoogle ScholarPubMed
Sadé, J. (1979) Clearance and the mucociliary system. In: Secretory Otitis Media and its Sequelae, Ed. Sadé, J.Churchill-Livingstone. London.Google Scholar
Torgersen, J. (1949) Genetic factors in visceral asymmetry and in the development and pathologic changes of lungs, heart and abdominal organs. Archives of Pathology, 47: 566593.Google Scholar
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